Reagents (3)

PD184352

Reference: SM73-100

€0.00 (tax incl.)

PD184352 has anti-cancer properties, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell (ESC) lines.

PD98059 inhibits cell growth and reverses the phenotype of ras-transformed BALB3T3 mouse fibroblasts and rat kidney cells. PD98059 inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines...

PD98059

Reference: SM28-10

€0.00 (tax incl.)

PD98059 inhibits cell growth and reverses the phenotype of ras-transformed BALB3T3 mouse fibroblasts and rat kidney cells. PD98059 inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines...

PD98059

Reference: SM28-25

€0.00 (tax incl.)

PD98059 inhibits cell growth and reverses the phenotype of ras-transformed BALB3T3 mouse fibroblasts and rat kidney cells. PD98059 inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines...

PD98059

Reference: SM28-50

€0.00 (tax incl.)

PD98059 inhibits cell growth and reverses the phenotype of ras-transformed BALB3T3 mouse fibroblasts and rat kidney cells. PD98059 inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines...

PI-103 Hydrochloride

Reference: SM74-2

€0.00 (tax incl.)

In blast cells, PI-103 inhibits leukemic proliferation, the clonogenicity of leukemic progenitors and induces mitochondrial apoptosis, especially in the compartment containing leukemic stem cells.

PI-103 Hydrochloride

Reference: SM74-10

€0.00 (tax incl.)

In blast cells, PI-103 inhibits leukemic proliferation, the clonogenicity of leukemic progenitors and induces mitochondrial apoptosis, especially in the compartment containing leukemic stem cells.

PI-103 Hydrochloride

Reference: SM74-25

€0.00 (tax incl.)

In blast cells, PI-103 inhibits leukemic proliferation, the clonogenicity of leukemic progenitors and induces mitochondrial apoptosis, especially in the compartment containing leukemic stem cells.

PI-103 Hydrochloride

Reference: SM74-100

€0.00 (tax incl.)

In blast cells, PI-103 inhibits leukemic proliferation, the clonogenicity of leukemic progenitors and induces mitochondrial apoptosis, especially in the compartment containing leukemic stem cells.

Pifithrin μ

Reference: SM29-2.5

€0.00 (tax incl.)

Pifithrin μ rescues cells from lethal γ-irradiation-induced cell death.

Pifithrin μ

Reference: SM29-10

€0.00 (tax incl.)

Pifithrin μ rescues cells from lethal γ-irradiation-induced cell death.

Pifithrin μ

Reference: SM29-50

€0.00 (tax incl.)

Pifithrin μ rescues cells from lethal γ-irradiation-induced cell death.

PIK-75 Hydrochloride

Reference: SM76-2

€0.00 (tax incl.)

This molecule inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and also activation of mTORC1. It has been studied that PIK-75 significantly reduces leukemia burden and increases the survival...

PIK-75 Hydrochloride

Reference: SM76-10

€0.00 (tax incl.)

This molecule inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and also activation of mTORC1. It has been studied that PIK-75 significantly reduces leukemia burden and increases the survival...

PIK-75 Hydrochloride

Reference: SM76-50

€0.00 (tax incl.)

This molecule inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and also activation of mTORC1. It has been studied that PIK-75 significantly reduces leukemia burden and increases the survival...

PIK-75 Hydrochloride

Reference: SM76-100

€0.00 (tax incl.)

This molecule inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and also activation of mTORC1. It has been studied that PIK-75 significantly reduces leukemia burden and increases the survival...

Plerixafor

Reference: SM78-2

€0.00 (tax incl.)

Plerixafor is one of the most efficient bone marrow stem cell mobilizers. Plerixafor results in the rapid and reversible mobilization of hematopoietic stem cells (HSC) into the peripheral circulation and is...

Plerixafor

Reference: SM78-10

€0.00 (tax incl.)

Plerixafor is one of the most efficient bone marrow stem cell mobilizers. Plerixafor results in the rapid and reversible mobilization of hematopoietic stem cells (HSC) into the peripheral circulation and is...

Plerixafor

Reference: SM78-25

€0.00 (tax incl.)

Plerixafor is one of the most efficient bone marrow stem cell mobilizers. Plerixafor results in the rapid and reversible mobilization of hematopoietic stem cells (HSC) into the peripheral circulation and is...

Plerixafor

Reference: SM78-50

€0.00 (tax incl.)

Plerixafor is one of the most efficient bone marrow stem cell mobilizers. Plerixafor results in the rapid and reversible mobilization of hematopoietic stem cells (HSC) into the peripheral circulation and is...

Plerixafor

Reference: SM78-200

€0.00 (tax incl.)

Plerixafor is one of the most efficient bone marrow stem cell mobilizers. Plerixafor results in the rapid and reversible mobilization of hematopoietic stem cells (HSC) into the peripheral circulation and is...

PP1

Reference: SM79-1

€0.00 (tax incl.)

PP1 inhibits anti-CD3-induced T cell tyrosine phosphorylation, TcR-induced T cell proliferation, and IL-2 gene induction. PP1 has been demonstrated to reduce the expression of vascular endothelial growth factor...

PP1

Reference: SM79-5

€0.00 (tax incl.)

PP1 inhibits anti-CD3-induced T cell tyrosine phosphorylation, TcR-induced T cell proliferation, and IL-2 gene induction. PP1 has been demonstrated to reduce the expression of vascular endothelial growth factor...

PP1

Reference: SM79-25

€0.00 (tax incl.)

PP1 inhibits anti-CD3-induced T cell tyrosine phosphorylation, TcR-induced T cell proliferation, and IL-2 gene induction. PP1 has been demonstrated to reduce the expression of vascular endothelial growth factor...

PTK787

Reference: SM80-5

€0.00 (tax incl.)

PTK787 inhibits VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival. It shows the anti-proliferation effect by inhibiting thymidine incorporation induced by VEGF in...

PTK787

Reference: SM80-25

€0.00 (tax incl.)

PTK787 inhibits VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival. It shows the anti-proliferation effect by inhibiting thymidine incorporation induced by VEGF in...

PTK787

Reference: SM80-100

€0.00 (tax incl.)

PTK787 inhibits VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival. It shows the anti-proliferation effect by inhibiting thymidine incorporation induced by VEGF in...

Purmorphamine

Reference: SM30-1

€0.00 (tax incl.)

Purmorphamine has been shown to induce osteogenesis in bone tissue as well as influencing growth and differentiation of neurons in the brain. The EC50 value for differentiation of C3H10T1/2 cells based on alkaline...

Purmorphamine

Reference: SM30-5

€0.00 (tax incl.)

Purmorphamine has been shown to induce osteogenesis in bone tissue as well as influencing growth and differentiation of neurons in the brain. The EC50 value for differentiation of C3H10T1/2 cells based on alkaline...

Purmorphamine

Reference: SM30-10

€0.00 (tax incl.)

Purmorphamine has been shown to induce osteogenesis in bone tissue as well as influencing growth and differentiation of neurons in the brain. The EC50 value for differentiation of C3H10T1/2 cells based on alkaline...

Rapamycin

Reference: SM83-5

€0.00 (tax incl.)

Rapamycin is a potent immunosuppressant and it has anticancer activity. It induces autophagy in yeast and mammalian cell lines. It is unique in its ability to inhibit lymphokine induced cell proliferation at the G1...

Rapamycin

Reference: SM83-25

€0.00 (tax incl.)

Rapamycin is a potent immunosuppressant and it has anticancer activity. It induces autophagy in yeast and mammalian cell lines. It is unique in its ability to inhibit lymphokine induced cell proliferation at the G1...

Rapamycin

Reference: SM83-50

€0.00 (tax incl.)

Rapamycin is a potent immunosuppressant and it has anticancer activity. It induces autophagy in yeast and mammalian cell lines. It is unique in its ability to inhibit lymphokine induced cell proliferation at the G1...

Rapamycin

Reference: SM83-100

€0.00 (tax incl.)

Rapamycin is a potent immunosuppressant and it has anticancer activity. It induces autophagy in yeast and mammalian cell lines. It is unique in its ability to inhibit lymphokine induced cell proliferation at the G1...

Rapamycin

Reference: SM83-1000

€0.00 (tax incl.)

Rapamycin is a potent immunosuppressant and it has anticancer activity. It induces autophagy in yeast and mammalian cell lines. It is unique in its ability to inhibit lymphokine induced cell proliferation at the G1...

Reboxetine Mesylate

Reference: SM84-2

€0.00 (tax incl.)

Reboxetine stimulates neural stem cell (NSC) expansion.

Reboxetine Mesylate

Reference: SM84-10

€0.00 (tax incl.)

Reboxetine stimulates neural stem cell (NSC) expansion.

Reboxetine Mesylate

Reference: SM84-25

€0.00 (tax incl.)

Reboxetine stimulates neural stem cell (NSC) expansion.

Reboxetine Mesylate

Reference: SM84-100

€0.00 (tax incl.)

Reboxetine stimulates neural stem cell (NSC) expansion.

Reversine

Reference: SM85-1

€0.00 (tax incl.)

Reversine is the first organic molecule that has been demonstrated to reverse the cellular differentiation process. It is shown to induce mouse C2C12 myoblast cells to become multipotent mesenchymal progenitor cells,...

Reversine

Reference: SM85-5

€0.00 (tax incl.)

Reversine is the first organic molecule that has been demonstrated to reverse the cellular differentiation process. It is shown to induce mouse C2C12 myoblast cells to become multipotent mesenchymal progenitor cells,...

Reversine

Reference: SM85-10

€0.00 (tax incl.)

Reversine is the first organic molecule that has been demonstrated to reverse the cellular differentiation process. It is shown to induce mouse C2C12 myoblast cells to become multipotent mesenchymal progenitor cells,...

RG108

Reference: SM31-2

€0.00 (tax incl.)

RG108 inhibits human tumor cell line (HCT116, NALM-6) proliferation and increased doubling time in culture.

RG108

Reference: SM31-10

€0.00 (tax incl.)

RG108 inhibits human tumor cell line (HCT116, NALM-6) proliferation and increased doubling time in culture.

RG108

Reference: SM31-50

€0.00 (tax incl.)

RG108 inhibits human tumor cell line (HCT116, NALM-6) proliferation and increased doubling time in culture.

Rosiglitazone

Reference: SM86-10

€0.00 (tax incl.)

Rosiglitazone is antidiabetic, working as an insulin sensitizer by binding to the PPAR gamma receptors in fat cells and making the cells more responsive to insulin. Rosiglitazone induced adipocyte differentiation in...

Rosiglitazone

Reference: SM86-50

€0.00 (tax incl.)

Rosiglitazone is antidiabetic, working as an insulin sensitizer by binding to the PPAR gamma receptors in fat cells and making the cells more responsive to insulin. Rosiglitazone induced adipocyte differentiation in...

Rosiglitazone

Reference: SM86-200

€0.00 (tax incl.)

Rosiglitazone is antidiabetic, working as an insulin sensitizer by binding to the PPAR gamma receptors in fat cells and making the cells more responsive to insulin. Rosiglitazone induced adipocyte differentiation in...

Rosiglitazone

Reference: SM86-1000

€0.00 (tax incl.)

Rosiglitazone is antidiabetic, working as an insulin sensitizer by binding to the PPAR gamma receptors in fat cells and making the cells more responsive to insulin. Rosiglitazone induced adipocyte differentiation in...

Ruxolitinib

Reference: SM87-2

€0.00 (tax incl.)

JAK inhibition with ruxolitinib could work as pretreatment for allogeneic stem cell transplantation in myelofibrosis. Ruxolitinib inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less...

Ruxolitinib

Reference: SM87-10

€0.00 (tax incl.)

JAK inhibition with ruxolitinib could work as pretreatment for allogeneic stem cell transplantation in myelofibrosis. Ruxolitinib inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less...

Ruxolitinib

Reference: SM87-25

€0.00 (tax incl.)

JAK inhibition with ruxolitinib could work as pretreatment for allogeneic stem cell transplantation in myelofibrosis. Ruxolitinib inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less...

Ruxolitinib

Reference: SM87-100

€0.00 (tax incl.)

JAK inhibition with ruxolitinib could work as pretreatment for allogeneic stem cell transplantation in myelofibrosis. Ruxolitinib inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less...

SAHA

Reference: SM88-10

€0.00 (tax incl.)

Experiments suggest that SAHA causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. SAHA alters gene transcription and induces cell cycle arrest and/or...

SAHA

Reference: SM88-50

€0.00 (tax incl.)

Experiments suggest that SAHA causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. SAHA alters gene transcription and induces cell cycle arrest and/or...

SAHA

Reference: SM88-250

€0.00 (tax incl.)

Experiments suggest that SAHA causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. SAHA alters gene transcription and induces cell cycle arrest and/or...

SAHA

Reference: SM88-500

€0.00 (tax incl.)

Experiments suggest that SAHA causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. SAHA alters gene transcription and induces cell cycle arrest and/or...

SAHA

Reference: SM88-1000

€0.00 (tax incl.)

Experiments suggest that SAHA causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. SAHA alters gene transcription and induces cell cycle arrest and/or...

SB203580

Reference: SM32-2

€0.00 (tax incl.)

SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating...

SB203580

Reference: SM32-10

€0.00 (tax incl.)

SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating...

SB203580

Reference: SM32-50

€0.00 (tax incl.)

SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating...

SB203580

Reference: SM32-100

€0.00 (tax incl.)

SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating...

SB216763

Reference: SM90-2

€0.00 (tax incl.)

SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...

SB216763

Reference: SM90-10

€0.00 (tax incl.)

SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...

SB216763

Reference: SM90-25

€0.00 (tax incl.)

SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...

SB216763

Reference: SM90-50

€0.00 (tax incl.)

SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...

SB216763

Reference: SM90-200

€0.00 (tax incl.)

SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...

SB431542

Reference: SM33-2

€0.00 (tax incl.)

SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...

SB431542

Reference: SM33-10

€0.00 (tax incl.)

SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...

SB431542

Reference: SM33-50

€0.00 (tax incl.)

SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...

SB431542

Reference: SM33-200

€0.00 (tax incl.)

SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...

SB590885

Reference: SM48-1

€0.00 (tax incl.)

In melanoma and colorectal cancer cell lines with B-Raf V600E mutation, an effective inhibition of cell proliferation was achieved by using SB590885 at concentrations that blocked ERK phosphorylation.

SB590885

Reference: SM48-5

€0.00 (tax incl.)

In melanoma and colorectal cancer cell lines with B-Raf V600E mutation, an effective inhibition of cell proliferation was achieved by using SB590885 at concentrations that blocked ERK phosphorylation.

SB590885

Reference: SM48-50

€0.00 (tax incl.)

In melanoma and colorectal cancer cell lines with B-Raf V600E mutation, an effective inhibition of cell proliferation was achieved by using SB590885 at concentrations that blocked ERK phosphorylation.

Sorafenib

Reference: SM95-10

€0.00 (tax incl.)

Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...

Sorafenib

Reference: SM95-50

€0.00 (tax incl.)

Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...

Sorafenib

Reference: SM95-500

€0.00 (tax incl.)

Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...

Sorafenib

Reference: SM95-1000

€0.00 (tax incl.)

Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...