SU5402

SU5402 is used in an embryonic stem cells (ESC) culture method with three inhibitors (3i: SU5402 for FGFR, PD184352 for ERK, and CHIR99021 for GSK3). It has been showed that this 3i method is extremely instrumental in establishing and culturing germline-competent ESC. It inhibits embryonic left-right determination and exhibits potent anticancer activity in-vitro and in-vivo.

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