Reagents (3)

GE81112 A/B

Reference: AG-CN2-0306

€0.00 (tax incl.)

Tetrapeptide antibiotic. Potent and selective inhibitor of bacterial protein synthesis. Translational inhibitor specific for the initiation phase. Binds to the 30S ribosomal subunit and specifically inhibits P-site...

NAI-107 [Microbisporicin]

Reference: AG-CN2-0307

€0.00 (tax incl.)

Antibacterial class I lantibiotic. Mixture of two similarly active and structurally related polypeptides (A1, 2246Da and A2, 2230Da) of 24 amino acids linked by 5 intramolecular thioether bridges. Inhibits cell wall...

NAI-108

Reference: AG-CN2-0308

€0.00 (tax incl.)

Antibacterial class I lantibiotic. Brominated variant of NAI-107 (AG-CN2-0307 https://adipogen.com/ag-cn2-0307-nai-107-microbisporicin.html ). Inhibits cell wall synthesis and consequently bacterial growth by forming...

NAI-112

Reference: AG-CN2-0309

€0.00 (tax incl.)

Labionin-containing class III lanthipeptide. Antinociceptive agent. Effective in animal models of nociceptic and inflammatory pain. Does not act through opioid, cannabinoid or descending adrenergic mechanisms. Most...

NAI-802

Reference: AG-CN2-0310

€0.00 (tax incl.)

Actagardin-related class II lantibiotic. Antibacterial with improved activity than actagardine against Staphylococcus spp. and Streptococcus spp. Shows significant activity against Gram-positive anaerobic bacteria,...

NAI-857

Reference: AG-CN2-0311

€0.00 (tax incl.)

Antibacterial class I lantibiotic. Inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key intermediate in peptidoglycan biosynthesis....

NAI-97 [Planosporicin]

Reference: AG-CN2-0312

€0.00 (tax incl.)

Antibacterial class I lantibiotic. Inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key intermediate in peptidoglycan biosynthesis....

Orthoformimycin

Reference: AG-CN2-0314

€0.00 (tax incl.)

Cinnamoyl aminoglycoside antibiotic. Protein synthesis inhibitor in vitro. Selective inhibitor of bacterial translation elongation, through binding to the 50S subunit. Inhibits EF-G-dependent mRNA translocation but...

Paramagnetoquinone A/B

Reference: AG-CN2-0315

€0.00 (tax incl.)

Potent antibacterial agent. Shows MIC values lower than 0.015µg/ml against Gram-positive pathogens, including some antibiotic-resistant strains and selected Gram-negative bacteria.

Pseudouridimycin

Reference: AG-CN2-0316

€0.00 (tax incl.)

Peptidyl nucleoside antibiotic. Selective nucleoside-analog inhibitor of bacterial RNA polymerase (RNAP). Inhibits RNAP through a distinctive binding site on RNAP (the NTP addition site) and mechanism (competition...

Purpuromycin

Reference: AG-CN2-0317

€0.00 (tax incl.)

Rubromycin antibiotic. Antibacterial, antifungal and anti-protozoal agent. Active against Gram-positive bacteria, Gram-negative bacteria and fungi. Telomerase inhibitor (IC50=3µM). Protein synthesis inhibitor. Binds...

Ramoplanin A2

Reference: AG-CN2-0318

€0.00 (tax incl.)

Glycolipodepsipeptide antibiotic. Complex of structurally related molecules A1, A2 and A3, with ramoplanin A2 as the primary component. Antibacterial and antiviral agent with activity against aerobic and anaerobic...

Rifamycin AF-K43033

Reference: AG-CN2-0320

€0.00 (tax incl.)

Ansamycin antibiotic. Hydrazone of 3-formylrifamycin SV. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).

Rifamycin AF

Reference: AG-CN2-0321

€0.00 (tax incl.)

Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and...

Rifamycin AF-K55517

Reference: AG-CN2-0322

€0.00 (tax incl.)

Ansamycin antibiotic. Hydrazone of 3-formylrifamycin SV. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).

Rifamycin AF-K56035

Reference: AG-CN2-0323

€0.00 (tax incl.)

Ansamycin antibiotic. Hydrazone of 3-formylrifamycin SV. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).

Rifamycin AF-K28259

Reference: AG-CN2-0324

€0.00 (tax incl.)

Ansamycin antibiotic. Hydrazone of 3-formylrifamycin SV. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).

Rifamycin AF-API

Reference: AG-CN2-0325

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin AF-EPTAPI

Reference: AG-CN2-0326

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin AF-K91725

Reference: AG-CN2-0327

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin AF-DA

Reference: AG-CN2-0328

€0.00 (tax incl.)

Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria. Therefore used in research of tuberculosis, leprosy and...

Rifamycin AG

Reference: AG-CN2-0329

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin AMI-DA

Reference: AG-CN2-0330

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin AMP-DA

Reference: AG-CN2-0331

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin M14

Reference: AG-CN2-0332

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin O

Reference: AG-CN2-0333

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin PR-14

Reference: AG-CN2-0334

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin PR-3

Reference: AG-CN2-0335

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin AF-O13

Reference: AG-CN2-0336

€0.00 (tax incl.)

Ansamycin antibiotic. Potent inhibitor of nucleic acid polymerizing enzymes and of some hormone receptors. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Inhibitor of RNA-dependent DNA...

Rifamycin S, 8-Methyl-

Reference: AG-CN2-0337

€0.00 (tax incl.)

Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC)...

Rifamycin AF-pNFI

Reference: AG-CN2-0338

€0.00 (tax incl.)

Ansamycin antibiotic. Hydrazone of 3-formylrifamycin SV. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).

Thermorubin

Reference: AG-CN2-0339

€0.00 (tax incl.)

Anthracene antibiotic. Antibacterial agent. Active against both Gram-positive and Gram-negative bacteria. Inhibits the initiation stage of bacterial protein synthesis by binding to the inter-subunit bridge B2a on the...

Asiatic acid

Reference: AG-CN2-0400

€0.00 (tax incl.)

Apoptosis inducer [1, 3]. Cell cycle arrest inducer [1]. Anticancer compound [1, 5] Antioxidant. Hepatoprotective [2]. Inhibits TGF-beta/Smad-mediated fibrogenesis [12]. Stimulates wound healing [4]. Anti-diabetic....

Sericic acid

Reference: AG-CN2-0402

€0.00 (tax incl.)

Anti-inflammatory [1]. Antibacterial [2, 3]. Antifungal [2]. Haemolytic agent [2]. Weak phosphodiesterase 4 (PDE4) inhibitor. [4]. Antioxidant [5].

Ledol

Reference: AG-CN2-0406

€0.00 (tax incl.)

Toxic sesquiterpenoid [1]. Exhibits expectorant and antitussive effect [1, 2]. Reported to increase blood pressure [2]. Antifungal compound [1].

(+)-Catechin . hydrate

Reference: AG-CN2-0407

€0.00 (tax incl.)

Specific histidine decarboxylase inhibitor [1]. Anti-inflammatory. COX-1 inhibitor [2]. Antioxidant flavonoid. Free radical scavenger. Inhibits lipid peroxidation [3, 6, 9]. Antimetastatic and anticancer compound [4,...

Rutin . trihydrate

Reference: AG-CN2-0408

€0.00 (tax incl.)

Antioxidant. Free radical scavenger. Nitric oxide (NO) scavenger [1, 5, 6]. Anticancer compound [2, 18]. Antiproliferative [10]. Apoptosis inducer [11]. Reduces induced DNA damage. Protective against carcinogenesis...

Quercetin . dihydrate

Reference: AG-CN2-0409

€0.00 (tax incl.)

Multipotent flavonoid antioxidant. Potent free radical scavenger. Neuroprotective. Anticancer compound with chemosensitizing activity. Cell cycle arrest, apoptosis and autophagy inducer. Proteasome inhibitor....

Chenodeoxycholic acid

Reference: AG-CN2-0410

€0.00 (tax incl.)

Cytotoxic hydrophobic primary bile acid [1]. Activator of farnesoid X receptor (FXR), a nuclear receptor that is hepatoprotective and regulates bile acid synthesis (cholesterol 7alpha-hydroxylase (CYP7A1)...

Ursodeoxycholic acid

Reference: AG-CN2-0411

€0.00 (tax incl.)

Endogenous hydrophilic bile acid. Antioxidant. Cytoprotective against oxidative stress and cell death. Hepatoprotective at cellular and molecular level, including stabilization of membranes. Protects hepatocytes...

Stigmasterol

Reference: AG-CN2-0412

€0.00 (tax incl.)

Anti-hypercholestrolemic compound [1, 7]. Anti-inflammatory and immune-modulating effects [2, 4]. Anticancer compound. Chemopreventive [3, 12, 13]. Cytostatic. Cell growth inhibitor [5]. Antimutagenic [6]. Potent in...

Meglumine

Reference: AG-CN2-0413

€0.00 (tax incl.)

Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell...

Papaverine . hydrochloride

Reference: AG-CN2-0414

€0.00 (tax incl.)

Smooth muscle relaxant and vasodilator [4]. Phosphodiesterase PDE10A inhibitor [3,5,6]. Antiviral [1,2]. Antipsychotic [3]. Potential inducer of browning in WAT.

Ionomycin (free acid)

Reference: AG-CN2-0416

€0.00 (tax incl.)

Antibiotic [1]. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators [2,...

Ionomycin . calcium salt

Reference: AG-CN2-0418

€0.00 (tax incl.)

Antibiotic [1]. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators [2,...

Mycophenolic acid

Reference: AG-CN2-0419

€0.00 (tax incl.)

Antibiotic [1]. Shows antiviral, antifungal and antitumor properties [1, 2]. Immunosuppressive drug used to prevent rejection in organ transplantation, rheumatoid arthritis, and psoriasis [3-6, 13]. Potent reversible...

Ascomycin (high purity)

Reference: AG-CN2-0420

€0.00 (tax incl.)

Macrolide antibiotic. Ethyl analog of FK506 [1, 2]. Strong immunosuppressant. Binds to the FK-506-binding protein FKBP12. This complex inhibits calcineurin (protein phosphatase 2B (PP2B)) [2-4, 8]. Suppresses the...

Epoxomicin

Reference: AG-CN2-0422

€0.00 (tax incl.)

Antibiotic [1]. Potent anticancer compound [1, 7]. Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits...

Butyrolactone II

Reference: AG-CN2-0423

€0.00 (tax incl.)

Antibiotic. Weak cytotoxic towards bacterial and cancer cell lines [1-3]. 5-Lipoxygenase (5-LOX) inhibitor [4, 5]. Shows DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavening activity [5].

Wedelolactone

Reference: AG-CN2-0424

€0.00 (tax incl.)

Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor [2]. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha [2]. Antihepatotoxic. 5-Lipoxygenase (5-LOX)...

Vitexin

Reference: AG-CN2-0425

€0.00 (tax incl.)

alpha-Glucosidase inhibitor [3, 8]. Antioxidant [1, 3]. HIF-1 alpha inhibitor [2]. Anti-metastatic [2, 13]. Apoptosis inducer [4, 9, 13]. Tumor suppressor [4, 9]. Adipogenesis inhibitor [5]. Inhibits SIRT6 in vitro...

Itaconic acid

Reference: AG-CN2-0426

€0.00 (tax incl.)

Mammalian antibacterial metabolite. Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth [1, 4]. Antimicrobial. Antibacterial [1, 3, 4]. Inhibits the growth of bacteria...

Genistein

Reference: AG-CN2-0427

€0.00 (tax incl.)

Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades [1]. Inhibitor of mammalian DNA...

Cinnamtannin B-1

Reference: AG-CN2-0428

€0.00 (tax incl.)

A-Type proanthocyanidine. Selective cytotoxic agent [1]. Potent antioxidant [2, 4, 8, 9]. Lipid peroxidation inhibitor [2]. Antidiabetic, with similar effects to insulin activity in adipogenesis [3]. Free radical...

Herbimycin A

Reference: AG-CN2-0429

€0.00 (tax incl.)

Benzoquinone ansamycin antibiotic. Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products....

Calphostin C

Reference: AG-CN2-0430

€0.00 (tax incl.)

Potent and highly specific cell permeable protein kinase C (PKC) inhibitor [1]. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor....

Ophiobolin A

Reference: AG-CN2-0431

€0.00 (tax incl.)

Cell permeable, irreversible calmodulin antagonist. Acts by covalently binding to a lysine-rich inhibitory site. Inhibits by blocking the activation of the Ca2+/calmodulin-dependent phosphodiesterase [1-3, 5, 6, 9]....

Eupatilin

Reference: AG-CN2-0432

€0.00 (tax incl.)

Selective inhibitor of 5-lipoxygenase. Anti-proliferative and anticancer compound. Apoptosis and cell cycle arrest inducer. Inhibits ERK1/2, JNK, and NF-kappaB activation and expression of Raf-1 and Ras. PI3K Class I,...

Helenalin

Reference: AG-CN2-0435

€0.00 (tax incl.)

Anticancer compound. NF-kappaB inhibitor. Apoptosis inducer. Potent anti-inflammatory agent. Telomerase inhibitor. Anti-trypanosomal and antiprotozoal compound Antibiotic. Shows anti-proliferative effects in 3T3-L1...

Altersolanol A

Reference: AG-CN2-0436

€0.00 (tax incl.)

Anticancer compound. Apoptosis inducer. Anti-angiogenic. Anti-inflammatory. Antibacterial. Phytotoxic.

Aloesin

Reference: AG-CN2-0437

€0.00 (tax incl.)

C-glycosylated chromone compound. Tyrosinase inhibitor. Inhibits melanin production. Inhibitor of hyperpigmentation. Antioxidant. Free radical scavenger. Anti-inflammatory compound. Shown to up-regulate cyclin E/CDK2...

Aloeresin A

Reference: AG-CN2-0439

€0.00 (tax incl.)

Metabolite of aloesin. alpha-Glucosidase inhibitor. Antioxidant. Free radical scavenger.

clasto-Lactacystin beta-lactone

Reference: AG-CN2-0442

€0.00 (tax incl.)

Potent and selective irreversible and cell permeable proteasome inhibitor. Inhibits the chymotrypsin-like, trypsin-like and caspase-like peptidase activity of the proteasome. The active metabolite of lactacystin...

Cyclosporin C

Reference: AG-CN2-0443

€0.00 (tax incl.)

Immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A (AG-CN2-0079). Antifungal. Antitumor.

Salinosporamide A

Reference: AG-CN2-0444

€0.00 (tax incl.)

Potent, irreversible inhibitor of all the 3 proteolytic activities of the mammalian 20S proteasome. beta5 subunit: chymotrypsin-like (EC50 = 3.5nM) beta2 subunit: trypsin-like (EC50 = 28nM) beta1 subunit: caspase-like...

Cyclosporin D

Reference: AG-CN2-0445

€0.00 (tax incl.)

Potent inhibitor of tumor promoting phorbol ester TPA/PMA (AG-CN2-0010) effects in vivo. Antifungal. Moderate immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A (AG-CN2-0079). Moderate...

Vincristine . sulfate

Reference: AG-CN2-0446

€0.00 (tax incl.)

Immunosuppressant. Anticancer compound. Chemotherapeutic agent. Depolymerizes microtubules and irreversibly blocks binding of tubulin to microtubule proteins. Apoptosis inducer and cell cycle inhibitor in G2/M phase....

Cyclosporin H

Reference: AG-CN2-0447

€0.00 (tax incl.)

Potent inhibitor of tumor promoting phorbol ester TPA/PMA (AG-CN2-0010) effects in vivo. Antifungal. Potent and effective inhibitor of formyl peptide receptor (FPR) and formyl peptide-induced superoxide formation....

Triptolide

Reference: AG-CN2-0448

€0.00 (tax incl.)

Potent immunosuppressant with anti-inflammatory and antitumor properties. Exhibits potent antiproliferative activity, induces apoptosis, modulates autophagy and inhibits cell cycle regulators. Inhibits global gene...

Hypericin

Reference: AG-CN2-0449

€0.00 (tax incl.)

One of the principal active constituents of St. John's Wort (Hypericum perforatum). Hypericin is a photosensitive pigment/chromophore with bright red fluorescence emission (lambdamax: 594nm). Has a high triplet...

Meleagrin

Reference: AG-CN2-0451

€0.00 (tax incl.)

Mycotoxin. Alkaloid antibiotic. Bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor. Antineoplastic activity. Moderate cytotoxicity against A-549 and HL-60 cell lines. Induces cell cycle arrest through...

Aerothionin

Reference: AG-CN2-0453

€0.00 (tax incl.)

Antibiotic. Anti-mycobacterial.

Vinpocetine

Reference: AG-CN2-0454

€0.00 (tax incl.)

Selective Ca2+-calmodulin dependent cGMP-phosphodiesterase (PDE1) inhibitor. Shows vasorelaxant activity. Neuroprotective agent. Selectively inhibits voltage-sensitive Na2+ channels Potent anti-inflammatory agent....

Parthenolide

Reference: AG-CN2-0455

€0.00 (tax incl.)

Anticancer and antiangiogenic compound. Induces apoptosis, cell cycle arrest and autophagy in various cancer cell lines. At low concentrations acts as antioxidant reducing oxidative stress generated through the TCR...

L-(-)-Camphoric acid

Reference: AG-CN2-0456

€0.00 (tax incl.)

Chirality inducing agent. Useful tool as resolving agent to separate the isomers and purify racemic mixtures (e.g. DL-lysine) by fractionally crystallizing the product to obtain the pure isomer (e.g. D-lysine). Can...

Emodin

Reference: AG-CN2-0457

€0.00 (tax incl.)

p56lck protein kinase inhibitor. Competitive casein kinase II (CK2) inhibitor. Anticancer agent with apoptosis inducing with antiangiogenic activity. Antioxidant, vasorelaxant and neuroprotective agent. NF-kappaB...

Arglabin

Reference: AG-CN2-0458

€0.00 (tax incl.)

Anticancer compound. Farnesyltransferase inhibitor. Potent anti-inflammatory agent. NF-kappaB inhibitor. Inflammasome inhibitor. Antiatherogenic. Prevents the accumulation of lipid containing plaques in arteries.

Isoliquiritigenin

Reference: AG-CN2-0459

€0.00 (tax incl.)

Anticancer. Apoptosis inducer and cell proliferation inhibitor. Autophagy inducer. Anti-angiogenic. VEGF/VEGFR-2 signaling inhibitor. Antioxidant and antibacterial. AMPK-mediated GSK3beta inhibitor. Anti-inflammatory....

Celastrol

Reference: AG-CN2-0460

€0.00 (tax incl.)

Anti-obesity agent. Potent leptin sensitizer. Antioxidant. Potent lipid peroxidation inhibitor. NADPH oxidases (NOX1, 2, 4 and 5) inhibitor. Anti-inflammatory. NF-kappaB inhibitor. HSP90 inhibitor and HSP70 inducer....

D-(+)-Camphoric acid

Reference: AG-CN2-0461

€0.00 (tax incl.)

Chirality inducing agent. Useful tool as resolving agent to separate the isomers and purify racemic mixtures (e.g. DL-lysine) by fractionally crystallizing the product to obtain the pure isomer (e.g. L-lysine). Can...

Amorfrutin A

Reference: AG-CN2-0462

€0.00 (tax incl.)

Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has nanomolar binding affinity to...

(S)-(+)-Camptothecin

Reference: AG-CN2-0463

€0.00 (tax incl.)

Potent anticancer compound. Cell permeable potent DNA topoisomerase I (Topo I) complex inhibitor. Potent apoptosis inducer. Binds reversibly to the DNA topoisomerase I complex, inhibiting the reassociation of DNA...

Amorfrutin B

Reference: AG-CN2-0464

€0.00 (tax incl.)

Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has low nanomolar binding affinity...

Convulxin

Reference: AG-CN2-0465

€0.00 (tax incl.)

Glycoprotein GPVI receptor agonist. Can be used for studies on platelet receptors. Activates mammalian platelets via binding and clustering of GPVI-receptors under physiological conditions. Occupation and clustering...

Theacrine

Reference: AG-CN2-0466

€0.00 (tax incl.)

Purine alkaloid related to caffeine. Potent antioxidant. Not through direct scavenging of ROS but strengthen antioxidant systems in vivo. Anti-inflammatory and antinociceptive compound. Suggested to have adenosine...

Artemisinin

Reference: AG-CN2-0467

€0.00 (tax incl.)

Anti-malaria. Apoptosis inducer. Anti-cancer. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Functional ARX...

Dihydroartemisinin

Reference: AG-CN2-0468

€0.00 (tax incl.)

Active metabolite of artemisinin. Anti-malaria (Plasmodium). Anti-schistosoma. Apoptosis inducer. Anti-cancer. Anti-inflammatory Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6),...

Artesunate

Reference: AG-CN2-0469

€0.00 (tax incl.)

Semi-synthetic derivative of artemisinin. Anti-malaria. Anti-schistosomiasis. Inhibitor of human cytomegalovirus (CMV). Apoptosis inducer. Anti-cancer. Immunosuppressant. Inhibits production of tumor necrosis...

Myxochelin A

Reference: AG-CN2-0470

€0.00 (tax incl.)

Potent inhibitor of human 5-lipoxygenase (5-LO). This enzyme catalyzes two initial steps in the conversion of arachidonic acid into leukotrienes, well known mediators of inflammatory and allergic reactions....

(-)-Viriditoxin

Reference: AG-CN2-0471

€0.00 (tax incl.)

Antibiotic. Exhibits broad activity against Gram-positive bacteria. Bacterial cell division protein FtsZ inhibitor (IC50=8.2µg/ml). Inhibits the GTPase activity of FtsZ in vitro (IC50=7.0µg/ml). Induces apoptosis and...

Cucurbitacin B

Reference: AG-CN2-0472

€0.00 (tax incl.)

Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation. Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties. Induces apoptosis, autophagy...

T-2 Toxin

Reference: AG-CN2-0473

€0.00 (tax incl.)

Common trichothecene mycotoxin, which can infect grain crops causing alimentary toxic aleukia in humans and animals. Inhibits DNA and RNA synthesis in vivo and in vitro and can induce apoptosis. In vivo the compound...

Cucurbitacin E

Reference: AG-CN2-0474

€0.00 (tax incl.)

Potent actin depolymerization inhibitor. Shown to have a different mechanism of action compared to jasplakinolide (Prod. No. AG-CN2-0037), binding to a different site. Binds specifically to filamentous actin (F-actin)...

Hellebrin

Reference: AG-CN2-0475

€0.00 (tax incl.)

Highly potent Na+/K+-ATPase inhibitor, blocking the active efflux of Na+ and reuptake of K+. Water soluble cardiotonic glycoside from the class of bufadienolides (with 2-pyrone ring). Inhibits cancer cell growth in...

Betulin

Reference: AG-CN2-0476

€0.00 (tax incl.)

Specific SREBPs (sterol regulatory element-binding proteins) inhibitor. Inhibits ER-Golgi translocation of SREBPs through binding to SCAP in an INSIG-dependent manner. Improves hyperlipidemia and insulin resistance...

Enniatin A

Reference: AG-CN2-0477

€0.00 (tax incl.)

Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms...

Enniatin A1

Reference: AG-CN2-0478

€0.00 (tax incl.)

Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms...

Enniatin B

Reference: AG-CN2-0479

€0.00 (tax incl.)

Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic (less ionophoric than Enniatin A). Incorporation...

Enniatin B1

Reference: AG-CN2-0480

€0.00 (tax incl.)

Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms...

Genipin

Reference: AG-CN2-0481

€0.00 (tax incl.)

Cell permeable inhibitor of uncoupling protein 2 (UCP2). Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Anticancer, antimetastatic and...

Category: Reagents

Menu

Settings