Stigmasterol

Anti-hypercholestrolemic compound [1, 7]. Anti-inflammatory and immune-modulating effects [2, 4]. Anticancer compound. Chemopreventive [3, 12, 13]. Cytostatic. Cell growth inhibitor [5]. Antimutagenic [6]. Potent in vitro antagonist of FXR (farnesoid X receptor) [8]. DNA polymerase beta inhibitor [9]. Potent antioxidant, hypoglycemic and thyroid inhibiting agent [10]. Anti-osteoarthritic. Decreases the expression of matrix metalloproteinases [11]. Neuroprotective [15]. Is used as a precursor for synthetic progesterone and vitamin D3 and is an intermediate in the biosynthesis of androgens, estrogens and corticoids [14].