Vinpocetine

Selective Ca2+-calmodulin dependent cGMP-phosphodiesterase (PDE1) inhibitor. Shows vasorelaxant activity. Neuroprotective agent. Selectively inhibits voltage-sensitive Na2+ channels Potent anti-inflammatory agent. Inhibitor of NF-kappaB-dependent inflammatory responses Inhibitor of IkappaB kinase IKK. Shown to inhibit the NLRP3 inflammasome. Antioxidant. Free radical scavenger. Anticancer compound. Anticonvulsant. Attenuates osteoblastic differentiation of vascular smooth muscle cells. Anti-schistosomal agent. Attenuates liver fibrosis