Asiatic acid
Apoptosis inducer [1, 3]. Cell cycle arrest inducer [1]. Anticancer compound [1, 5] Antioxidant. Hepatoprotective [2]. Inhibits TGF-beta/Smad-mediated fibrogenesis [12]. Stimulates wound healing [4]. Anti-diabetic. Glycogen phosphorylase inhibitor [6]. Neuroprotective [13]. Modulates multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance. Down regulates BACE1 and increases ADAM10 maturation [7]. Anti-hyperglycemic compound [8, 14]. Anti-inflammatory and antinociceptive compound [9]. Antiangiogenic [10]. Acetylcholinesterase (AChE) inhibitor [11]. PPARgamma inhibitor through a C/EBPbeta-independent mechanisms [15]. Anti-osteoporotic. Inhibits adipogenic differentiation of bone marrow stromal cells (BMSC) [15].
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Reference:
AG-CN2-0400
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