Reagents (2)

Cyclosporin A

Reference: AG-CN2-0079

€0.00 (tax incl.)

Potent immunosuppressant (same as FK-506 (Prod. No. AG-CN2-0047) and rapamycin (Prod. No. AG-CN2-0025)). Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase...

Asiaticoside

Reference: AG-CN2-0080

€0.00 (tax incl.)

Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and...

4alpha-Phorbol 12-myristate 13-acetate

Reference: AG-CN2-0082

€0.00 (tax incl.)

Negative control for phorbol ester activation of protein kinase C and studies with PMA (AG-CN2-0010) [1-6]. Might be a reasonable PKC-independent TRPV4 channels agonist [5].

Pseudolaric acid B

Reference: AG-CN2-0083

€0.00 (tax incl.)

Antifungal and antifertility compound [1, 3]. Antitumor compound [2, 7-9, 13]. PPARalpha signaling agonist [4]. Angiogenesis inhibitor [5, 6, 11]. Apoptosis and autophagy inducer [7, 9, 15, 17]....

Imperatorin

Reference: AG-CN2-0084

€0.00 (tax incl.)

Anticancer compound [1, 2, 10, 14]. Apoptosis inducer. Induces DNA fragmentation at the G1/S phase of the cell cycle [1, 2, 14]. HIV-1 replication inhibitor [3]. Anti-inflammatory [4, 9, 11]. Vasodilatation inducer...

Umbellulone

Reference: AG-CN2-0085

€0.00 (tax incl.)

Offensive principle of the so-called "headache tree". Causes a painful cold sensation. Selective TRPA1 activator. Weak TRPM8 activator. Releases CGRP (calcitonin gene-related peptide) after TRPA1 activation which...

Piceatannol

Reference: AG-CN2-0086

€0.00 (tax incl.)

Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K [1-3, 9, 14, 15]. Inhibits the tyrosine phosphorylation of STAT3 and STAT5 [4]. Potent...

Apicidin

Reference: AG-CN2-0087

€0.00 (tax incl.)

Antiprotozoal [1]. Potent inhibitor of histone deacetylase (HDAC) [1,2]. Inhibits proliferation [2,3]. Induces cell cycle arrest at the G1 phase [2]. Induces hyperacetylation of histone H4 [5]. Apoptosis inducer...

Psammaplin A

Reference: AG-CN2-0088

€0.00 (tax incl.)

Antibiotic [1]. Caffeine-like Ca2+ releaser in heavy sarcoplasmic reticulum (HSR) [2]. Antifungal [3]. Chitinase inhibitor [3]. DNA methyltransferase inhibitor [4]. Histone deacetylase (HDAC) inhibitor [4, 5]....

Forskolin

Reference: AG-CN2-0089

€0.00 (tax incl.)

Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels [1, 2, 6]. Widely used tool to investigate cAMP as a second messenger [15]. Inotropic and antihypertensive. Smooth muscle...

Xanthorrhizol

Reference: AG-CN2-0090

€0.00 (tax incl.)

Shows calcium-antagonistic and vasorelaxant activity [1,3]. Antibacterial [2]. Anti-inflammatory. Potent COX-2 and inducible nitric oxide (iNOS; NOS II) inhibitor [4,5,9]. Hepatoprotective [5, 6]. Anticancer compound....

Heliquinomycin

Reference: AG-CN2-0091

€0.00 (tax incl.)

Antibiotic [1]. DNA helicase inhibitor [1]. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex [3, 4]. Topoisomerase I and II inhibitor (weaker than DNA helicase) [2]. DNA...

Rubratoxin A

Reference: AG-CN2-0092

€0.00 (tax incl.)

Mycotoxin [1]. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP [2]. Antitumor agent. Antimetastatic [2].

Cytostatin

Reference: AG-CN2-0093

€0.00 (tax incl.)

Potent and selective protein phosphatase 2A (PP2A) inhibitor [4-7]. Cell adhesion inhibitor [1]. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to...

K-252c

Reference: AG-CN2-0097

€0.00 (tax incl.)

Indolocarbazole alkaloid antibiotic. [1]. Potent cell permeable reversible and ATP-competitive PKC (protein kinase C) inhibitor with 10-fold selectivity over PKA (protein kinase A) [1-5]. Anticancer compound....

Luteolin

Reference: AG-CN2-0098

€0.00 (tax incl.)

Anticancer and antimetastatic agent that induces apoptosis and modulates autophagy. Shown to inhibits kinase signalling, including PKC(epsilon) and Src kinase, HDAC, Phosphatidylinositol 3-kinase (PI3K) / Akt and p90...

Atpenin A5

Reference: AG-CN2-0100

€0.00 (tax incl.)

Antibiotic [1-3]. Antifungal [1-3]. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor [4, 5, 7]. Mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator [6, 8]....

Citrinin

Reference: AG-CN2-0101

€0.00 (tax incl.)

Antibiotic [1, 2]. Antiprotozoal. Antimicrobial [3, 6]. Cytotoxic and genotoxic in various mammalian cells [4]. Mitochondrial permeability transition pore (MPTP) activator [5-7]. Apoptosis inducer [7-9, 14]. ERK and...

EM574

Reference: AG-CN2-0102

€0.00 (tax incl.)

Shows strong gastrointestinal motor stimulating (GMS) activity [1, 2, 5]. Motilin receptor agonist [3, 6]. Stimulates smooth muscle cell contraction [3]. Stimulates cholinergic neurons in a non-vagal pathway [4]....

(R,R)-Hymeglusin

Reference: AG-CN2-0103

€0.00 (tax incl.)

beta-Lactone antibiotic [1]. Antibacterial and antifungal [1, 4]. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active...

Lactacystin

Reference: AG-CN2-0104

€0.00 (tax incl.)

Induces neuritogenesis [1, 3]. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex) [2, 4, 7]. Blocks proteasome activity by targeting the...

Prodigiosin

Reference: AG-CN2-0105

€0.00 (tax incl.)

Red-pigmented antibiotic [1]. Antimalarial [2, 13]. Immunosuppressive [3, 7, 11, 12]. Apoptosis inducer [4-6, 15]. Cytotoxic. Induces phosphorylation of p38-MAPK [8]. Antimetastatic. Tumor invasion inhibitor [9]....

Pyripyropene A

Reference: AG-CN2-0106

€0.00 (tax incl.)

Antibiotic [1]. Highly specific inhibitor of acyl-coenzyme A:cholesterol acetyltransferase 2 (ACAT2) [1-6, 8, 9]. Anti-angiogenic [10]. Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and...

Malformin C

Reference: AG-CN2-0107

€0.00 (tax incl.)

Peptide antibiotic [1]. Induces root curvature and malformation in plants [1]. Antibacterial [1, 2], antimalarial and antitrypanosomal [4]. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to...

Amidepsine A

Reference: AG-CN2-0109

€0.00 (tax incl.)

Diacylglycerol acyltransferase (DGAT) inhibitor [1-4]. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes...

Amidepsine D

Reference: AG-CN2-0110

€0.00 (tax incl.)

Diacylglycerol acyltransferase (DGAT) inhibitor [1-4]. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes...

Cercosporin

Reference: AG-CN2-0111

€0.00 (tax incl.)

Phytotoxin [1, 4]. Potent and specific PKC inhibitor. Competes for the phorbol binding site [2, 3, 6]. Anticancer compound. Cytotoxic [5, 6, 7]. Antiproliferative [5, 6]. Antiparasitic [7, 8]. Antimicrobial [8]....

1233B

Reference: AG-CN2-0112

€0.00 (tax incl.)

Hydroxy-acid of antibiotic 1233A. Antibiotic. Antibacterial. Shows low toxicity on zebrafish embryos (48h, 10 µM).

Amauromine

Reference: AG-CN2-0113

€0.00 (tax incl.)

Antibiotic. Hypotensive vasodilator. Calcium channel antagonist. Potent and selective CB1 receptor antagonist.

Aranorosin

Reference: AG-CN2-0114

€0.00 (tax incl.)

Antibiotic [1, 2]. Antibacterial [1-6]. Antifungal [1-6]. Anticancer compound [3, 4]. Inhibits anti-apoptotic functions regulated by Bcl-2 [7]. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the...

Dihydrochlamydocin

Reference: AG-CN2-0115

€0.00 (tax incl.)

Phytotoxin [1-3, 5]. Derivative of HDAC inhibitor chlamydocin [1-3, 5] Similar chemical structure to the TAN-1746 compounds (potent HDAC inhibitors) [4].

Enterocin

Reference: AG-CN2-0116

€0.00 (tax incl.)

Potent antibiotic. Bacteriocin. Antibacterial. Broad spectrum activity against Gram-positive and Gram-negative bacteria. Herbicidal. Enterocin is a small molecular weight secondary metabolite and should not be...

Harzianum A

Reference: AG-CN2-0117

€0.00 (tax incl.)

Antifungal [1]. Anticancer compound. Cytotoxic to human cancer cell lines [2, 3].

Heptelidic acid

Reference: AG-CN2-0118

€0.00 (tax incl.)

Antibiotic [1, 2]. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GAPDH [3-7, 10, 11]. Anticancer compound [8]. Selectively...

17-Hydroxyventuricidin A

Reference: AG-CN2-0119

€0.00 (tax incl.)

Antifungal [1, 2]. Antibacterial against Gram-positive bacteria [1, 2].

Lariatin A

Reference: AG-CN2-0120

€0.00 (tax incl.)

Peptide with lasso structure. Antimycobacterial.

11-O-Methylpseurotin A

Reference: AG-CN2-0121

€0.00 (tax incl.)

Antibacterial. Selectively inhibits a Hof1 deletion strain.

Penicillide

Reference: AG-CN2-0122

€0.00 (tax incl.)

Plant growth inhibitor [1]. Mycotoxin. Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor [3, 6]. Anticancer compound. Cytotoxic [4]. Non-peptidic oxytocin receptor antagonist [5]. Calpain inhibitor [7].

Pyridoxatin

Reference: AG-CN2-0123

€0.00 (tax incl.)

Antibiotic [1, 2]. Free radical scavenger [1]. Lipid peroxidation inhibitor [1]. Antimicrobial activity against Candida albicans [1]. Gelatinase A (MMP-2) inhibitor [3]. Anticancer. Cytotoxic [3]. DNA synthesis...

Rugulosin

Reference: AG-CN2-0124

€0.00 (tax incl.)

Antibiotic [1]. Antibacteriophage. Antiviral [2]. Mycotoxin [3]. DNA replication, transcription and repair inhibitor [4]. Antibacterial [5]. RNA polymerase and ribonuclease H inhibitor [6]. Insecticidal. Cytotoxic...

Terpendole C

Reference: AG-CN2-0125

€0.00 (tax incl.)

Acyl-CoA:cholesterol acyltransferase (ACAT) isozymes ACAT1 and ACAT2 inhibitor [1-3, 6]. Tremorgenic [4, 5]. Cholesteryl ester (CE) synthesis inhibitor [6, 7].

Viridiol

Reference: AG-CN2-0126

€0.00 (tax incl.)

Steroidal antibiotic. Belongs to the Viridin family, including Wortmannin (Prod. No. AG-CN2-0023 http://www.adipogen.com/ag-cn2-0023/wortmannin.html ). Antifungal. Phytotoxin. Shows necrotic activity on plants....

Terpendole E

Reference: AG-CN2-0127

€0.00 (tax incl.)

Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor [1, 2]. Mitotic kinesin Eg5 (Mitotic Kinesin Spindle Protein; KSP) inhibitor [3-7]. Specific M phase inhibitor [4].

Zelkovamycin

Reference: AG-CN2-0128

€0.00 (tax incl.)

Cyclic peptide antibiotic Antibacterial.

Ambuic acid

Reference: AG-CN2-0129

€0.00 (tax incl.)

Antibiotic. Antibacterial Antifungal. Inhibits the biosynthesis of cyclic peptide quormones in Gram-positive bacteria. Lead compound for antipathogenic drugs that target the quorum-sensing-mediated virulence...

Bikaverin

Reference: AG-CN2-0130

€0.00 (tax incl.)

Antibiotic [1]. Antiprotozoal [1]. Antifungal [2]. Anticancer [3-7]. ATP synthesis inhibitior [3, 4]. Haemolytic agent [5]. Antioomycete [8]. Spermidine-induced autoactivation inhibitor [9]. Plasma hyaluronan-binding...

Calpinactam

Reference: AG-CN2-0131

€0.00 (tax incl.)

Specific anti-mycobacterial. Inhibits growth of Mycobacteria smegmatis but also Mycobacteria tuberculosis. M. smegmatis is used as a model for mycobacterial species. It is useful for the research analysis of other...

Aspterric acid

Reference: AG-CN2-0132

€0.00 (tax incl.)

Antibiotic [1]. Pollen growth and development inhibitor [2-4].

Aurodox

Reference: AG-CN2-0133

€0.00 (tax incl.)

Antibiotic [2,3] Protein biosynthesis inhibitor by binding to elongation factor Tu (EF-Tu) [4-7]. Type 3 secretion system (T3SS) inhibitor [8]. Growth promotor in poultry [1].

Cyclopenin

Reference: AG-CN2-0134

€0.00 (tax incl.)

Antimicrobial [1,2]. Phytotoxic [3]. Specific acetylcholinesterase (AChE) inhibitor [4].

Fulvic Acid

Reference: AG-CN2-0135

€0.00 (tax incl.)

Free radical scavenger and antioxidant [1]. Potential compound to neutralize radioactive and toxic wastes and "heal" soils. Chelates and binds scores of minerals into a bioavailable form used by cells [1]. Shown to...

Cyclopenol

Reference: AG-CN2-0136

€0.00 (tax incl.)

Antimicrobial [1]. Phytotoxic [1,2].

Funalenone

Reference: AG-CN2-0137

€0.00 (tax incl.)

Matrix metalloproteinase-1 (MMP-1; Type I collagenase) inhibitor [1]. HIV-1 integrase inhibitor [2].

Fuscin

Reference: AG-CN2-0138

€0.00 (tax incl.)

Mycotoxin. Antibacterial agent. ADP transport inhibitor. NADH dehydrogenase (NADH-Coenzyme Q oxidoreductase; Complex I) inhibitor. Inhibits mitochondrial respiration and oxidative phosphorylation (OXPHOS). Human CCR5...

Geodin

Reference: AG-CN2-0139

€0.00 (tax incl.)

Plasminogen activator inhibitor (PAI-1) [1]. Glucose uptake stimulator [2].

Palitantin

Reference: AG-CN2-0140

€0.00 (tax incl.)

Antiprotozoal (Leishmania) [1]. Antifungal [2].

Streptochlorin

Reference: AG-CN2-0141

€0.00 (tax incl.)

Antibiotic [1]. TNF-alpha-induced NF-kappaB activation inhibitor [1]. Antiangiogenic [1]. Apoptosis inducer [2-4]. Anticancer compound. Selective cytotoxic against several cancer cell lines [2-4]. Tyrosinase inhibitor...

Territrem B

Reference: AG-CN2-0142

€0.00 (tax incl.)

Tremorgenic mycotoxin [1, 2]. Potent and specific, irreversible acetylcholinesterase (AChE) inhibitor [3-7].

Altenusin

Reference: AG-CN2-0143

€0.00 (tax incl.)

Antibiotic [7]. Antifungal penicillide [8]. Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor [2]. Strong pp60c-Src inhibitor [3]. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor...

Andrastin A

Reference: AG-CN2-0144

€0.00 (tax incl.)

Mycotoxin [1, 5, 7, 8]. Protein farnesyltransferase (PFTase) inhibitor [1-3]. Anti-cancer compound [1-3]. Directly interacts with P-glycoprotein and inhibits the efflux of antitumor agents in drug resistant cells [4, 6].

Aspergillimide

Reference: AG-CN2-0145

€0.00 (tax incl.)

Antibiotic [1]. Anthelmintic agent [1]. Paralytic against Bombyx mori [2, 3].

Siamycin I

Reference: AG-CN2-0146

€0.00 (tax incl.)

Antibiotic [1]. Lariat peptide antiviral [1]. Anti-HIV and anti-HSV (Herpes simplex virus) agent [4-6]. Fsr quorum sensing inhibitor [7-9]. Calmodulin-activated myosin light chain kinase (MLCK) inhibitor [2, 3].

Curvularin

Reference: AG-CN2-0147

€0.00 (tax incl.)

Antibiotic [1]. Antiprotozoal [1]. Antifungal and phytotoxic compound [1, 6]. Anti-inflammatory [7]. TGF-beta signaling inhibitor [8] Anticancer compound [2, 9]. Inhibits expression of inducible nitric oxide synthase...

Cycloaspeptide A

Reference: AG-CN2-0148

€0.00 (tax incl.)

Antibiotic [1, 2]. Antimalaria agent [2].

Harzianopyridone

Reference: AG-CN2-0149

€0.00 (tax incl.)

Antibiotic [1]. Antifungal and antibacterial compound [1, 2, 6]. Specific mitochondrial complex II (succinate ubiquinone oxidoreductase; succinate dehydrogenase) inhibitor [3, 5]. Herbicidal activity [4]. Anthelmintic...

Nocardamine

Reference: AG-CN2-0150

€0.00 (tax incl.)

Antibiotic [1, 6]. Anti-mycobacterial [7]. Siderophore (iron (Fe) chelating compound) [5, 8]. Inducer of morphological changes in insect cells [3]. Antioxidant [4]. Anticancer compound [2, 8].

16-keto-Aspergillimide

Reference: AG-CN2-0151

€0.00 (tax incl.)

Antibiotic [1]. Anthelmintic agent [1].

Macrosphelide A

Reference: AG-CN2-0152

€0.00 (tax incl.)

Antibiotic [1, 2]. Cell-cell adhesion inhibitor [1, 2]. Antimetastatic compound [1, 2, 5]. Antifungal [3]. Antimicrobial [4].

Neoxaline

Reference: AG-CN2-0154

€0.00 (tax incl.)

Antimitotic. Cell cycle inhibitor at the G2/M phase [3, 4]. Antiproliferative [3]. Weak CNS stimulant with weak inhibitory activity on blood platelet aggregation [1, 2]. Mycotoxin [1].

NG 012

Reference: AG-CN2-0155

€0.00 (tax incl.)

Antibiotic. Mycotoxin. Very weak cytotoxic activity. Antifungal. Inhibits cell wall biosynthesis. Nerve growth factor (NGF) potentiator.

Pyranonigrin A

Reference: AG-CN2-0156

€0.00 (tax incl.)

Antioxidant. Radical scavenging activity towards DPPH and superoxide [3]. Shows a suppressive effect on the expression of vascular cell adhesion molecule-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs)...

Virustomycin A

Reference: AG-CN2-0157

€0.00 (tax incl.)

Antibiotic [1, 3, 4]. Anti-viral compound [1]. Antifungal (weak) [2]. Anti-protozoal (Trypanosoma, Trichomonas) [2, 5].

OM173-alphaA

Reference: AG-CN2-0158

€0.00 (tax incl.)

Antibiotic [1-3]. Antimycoplasma [1, 3, 4]. Antifungal compound [1, 3]. Anti-malarial agent [5]. Ras-competitive non-CAAX mimetic type farnesyltransferase (FTase) inhibitor [6]. Potential anticancer compound. Inducer...

Martinomycin

Reference: AG-CN2-0159

€0.00 (tax incl.)

Antibiotic [1-3]. Active against Gram-positive bacteria [1, 2]. Active against Spodoptera eridania [1, 2].

Thailandolide B

Reference: AG-CN2-0160

€0.00 (tax incl.)

Antibiotic [1]. Stereoisomer of chrodrimanin B, which is an insecticidal compound [2].

Actinonin

Reference: AG-CN2-0161

€0.00 (tax incl.)

Antibiotic. Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor. Potent peptide deformylase (PDF) inhibitor. Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not...

Aspergillin PZ

Reference: AG-CN2-0162

€0.00 (tax incl.)

Antibiotic [1]. Inducer of morphological deformation of the conidia of Pyricularia oryzae [1].

epi-Aszonalenin A

Reference: AG-CN2-0163

€0.00 (tax incl.)

Derivative of aszonalenin, a substance P inhibitor.

Quinolactacin A

Reference: AG-CN2-0164

€0.00 (tax incl.)

Antibiotic [1-3]. Acetylcholinesterase (AChE) inhibitor [3]. Anti-inflammatory compound [1, 4]. Tumor necrosis factor (TNF) inhibitor [1, 4].

10,11-Dehydrocurvularin

Reference: AG-CN2-0165

€0.00 (tax incl.)

Antibiotic [1, 2, 6]. Antifungal [6]. Nematicidal [4]. Phytotoxic [3]. TGF-beta signaling inhibitor [9] Anticancer compound [5, 6, 8, 10]. Strong activator of the heat shock response [8]. Inhibitor of the appressorium...

Boromycin

Reference: AG-CN2-0166

€0.00 (tax incl.)

Boron-containing macrolide antibiotic [1]. Antibacterial [1]. Antiprotozoal (Plasmodium, Babesia) [2]. Anti-HIV compound [3,6]. Ca2+ homeostasis modulator [4]. Potentiator of bleomycin-induced anti-tumor activity [5]....

Paxilline

Reference: AG-CN2-0167

€0.00 (tax incl.)

Tremorgenic [1]. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels [2]. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)) [3]....

Aspochalasin I

Reference: AG-CN2-0168

€0.00 (tax incl.)

Cytotoxic. Melanogenesis inhibitor without cytotoxicity.

Malformin A1

Reference: AG-CN2-0169

€0.00 (tax incl.)

Peptide antibiotic. Antibcaterial [1]. Plant growth stimulator [2]. Induces root curvature and malformation in plants [3]. Mycotoxin [4]. Prevents interleukin-1 (IL-1) induced endothelial changes by inhibition of...

Herquline A

Reference: AG-CN2-0170

€0.00 (tax incl.)

Weak blood platelet aggregation inhibitor compared to Herquline B.

Asperphenamate

Reference: AG-CN2-0171

€0.00 (tax incl.)

Anticancer compound. Cytotoxic against human breast cancer cells. Induces autophagic cell death in MCF-7 cells. Moderate radical scavenger. Weak acetylcholinesterase (AChE) inhibitor. Shows moderate trypanocidal...

Viridicatumtoxin

Reference: AG-CN2-0172

€0.00 (tax incl.)

Mycotoxin. Tetracycline antibiotic. Potent antibacterial agent with activity against several strains of Staphylococcus aureus, including Methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA)....

Rasfonin

Reference: AG-CN2-0173

€0.00 (tax incl.)

Selective apoptosis inducer in ras-dependent cells. Autophagy (Akt-dependent), apoptosis and necroptosis inducer in renal cancer cell lines. Induces death of ras-mutated pancreatic tumor (Panc-1) cells in vitro and in...

Globosuxanthone A

Reference: AG-CN2-0174

€0.00 (tax incl.)

Potent anticancer agent. Inhibits cell growth, proliferation and survival of human tumor cells lines in vivo and in vitro. Exhibits strong cytotoxicity against a panel of human solid tumor cell lines, disrupting the...

Bostrycin

Reference: AG-CN2-0175

€0.00 (tax incl.)

Anthraquinone antibiotic. Red antibacterial agent against Gram positive bacteria. Anticancer agent. Inhibits cell proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt pathway. Also shown...

Roridin E

Reference: AG-CN2-0176

€0.00 (tax incl.)

Mycotoxin. Implicated in human and animal toxicosis. Potent cytotoxic and antiproliferative agent against cancer cell lines. Potent antimalarial agent. Antifungal, antibiotic, phototoxic and cytostatic agent....

Actagardin

Reference: AG-CN2-0300

€0.00 (tax incl.)

Tetracyclic class II lantibiotic. Structurally related to mersacidine. Antibiotic. Antibacterial against Gram-positive bacteria and Gram-negative microorganisms. Specifically inhibits peptidoglycan synthesis in the...

BE-31405

Reference: AG-CN2-0302

€0.00 (tax incl.)

Broad spectrum antifungal agent compared to sordarin. Shows growth inhibitory activity against pathogenic fungal strains such as Candida albicans, C. glabrata and Cryptococcus neoformans. Inhibits the protein...

GE2270A

Reference: AG-CN2-0303

€0.00 (tax incl.)

Thiopeptide antibiotic. Antibacterial agent by inhibiting bacterial protein synthesis. Active against numerous Gram-positive pathogens, including methicillin-resistant strains of Staphylococcus aureus and...

GE2270 D2

Reference: AG-CN2-0304

€0.00 (tax incl.)

Thiopeptide antibiotic. Congener of GE2270A (AG-CN2-0303 https://adipogen.com/ag-cn2-0303-ge2270a.html ). Used as a starting scaffold bearing a free hydroxy group, for the production of new interesting semi-synthetic...

GE23077 A1/B1

Reference: AG-CN2-0305

€0.00 (tax incl.)

Cyclic heptapeptide antibiotic. Potent and selective inhibitor of bacterial RNA polymerase (RNAP). Inhibits Gram-positive (Bacillus subtilis) and Gram-negative (Escherichia coli) RNAPs with IC50 ~20nM, whereas it is...

GE81112 A/B

Reference: AG-CN2-0306

€0.00 (tax incl.)

Tetrapeptide antibiotic. Potent and selective inhibitor of bacterial protein synthesis. Translational inhibitor specific for the initiation phase. Binds to the 30S ribosomal subunit and specifically inhibits P-site...

NAI-107 [Microbisporicin]

Reference: AG-CN2-0307

€0.00 (tax incl.)

Antibacterial class I lantibiotic. Mixture of two similarly active and structurally related polypeptides (A1, 2246Da and A2, 2230Da) of 24 amino acids linked by 5 intramolecular thioether bridges. Inhibits cell wall...

NAI-108

Reference: AG-CN2-0308

€0.00 (tax incl.)

Antibacterial class I lantibiotic. Brominated variant of NAI-107 (AG-CN2-0307 https://adipogen.com/ag-cn2-0307-nai-107-microbisporicin.html ). Inhibits cell wall synthesis and consequently bacterial growth by forming...

NAI-112

Reference: AG-CN2-0309

€0.00 (tax incl.)

Labionin-containing class III lanthipeptide. Antinociceptive agent. Effective in animal models of nociceptic and inflammatory pain. Does not act through opioid, cannabinoid or descending adrenergic mechanisms. Most...

Category: Reagents

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