Malformin A1

Peptide antibiotic. Antibcaterial [1]. Plant growth stimulator [2]. Induces root curvature and malformation in plants [3]. Mycotoxin [4]. Prevents interleukin-1 (IL-1) induced endothelial changes by inhibition of protein synthesis [5]. Inhibitor of interleukin-1 beta (IL1 beta) binding to its receptor [6]. Enhancer of cellular fibrinolytic activity [7, 12]. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents [8]. Anticancer compound. Cytotoxic against several cancer cell lines [9]. Antimalarial and antitrypanosomal [10]. Inhibitor of BRAF-mutated melanoma cell lines [11].