Quote (R,R)-Hymeglusin
beta-Lactone antibiotic [1]. Antibacterial and antifungal [1, 4]. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme [2-4, 6-8]. Mevalonate biosynthesis inhibitor [5].
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Reference:
AG-CN2-0103
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