Reagents (2)

Dexamethasone

Reference: SM47-1000

€0.00 (tax incl.)

Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dorsomorphin Dihydrochloride

Reference: SM03-2

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-10

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-50

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-200

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Fasudil Hydrochloride

Reference: SM49-10

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-50

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-250

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-500

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-1000

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Forskolin

Reference: SM18-2

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-10

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-50

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-100

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-1000

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Garcinol

Reference: SM52-1

€0.00 (tax incl.)

Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

Garcinol

Reference: SM52-5

€0.00 (tax incl.)

Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

Garcinol

Reference: SM52-25

€0.00 (tax incl.)

Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

GDC-0449

Reference: SM54-5

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-25

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-50

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-200

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0941

Reference: SM19-2

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-10

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-25

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-50

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-200

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

Geldanamycin

Reference: SM55-2

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-10

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-25

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-50

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-250

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Go 6983

Reference: SM20-1

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

Go 6983

Reference: SM20-5

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

Go 6983

Reference: SM20-10

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

GSK429286A

Reference: SM21-2

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GSK429286A

Reference: SM21-10

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GSK429286A

Reference: SM21-50

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GX15-070

Reference: SM56-2

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-10

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-50

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-200

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

ID-8

Reference: SM01-1

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-5

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-50

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-100

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

IM-12

Reference: SM04-2

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-10

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-25

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-100

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-500

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-5

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-25

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-100

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-250

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-1000

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

IWP-2

Reference: SM39-2

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

IWP-2

Reference: SM39-10

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

IWP-2

Reference: SM39-50

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

IWP-2

Reference: SM39-100

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

JNJ-10198409

Reference: SM62-1

€0.00 (tax incl.)

JNJ-10198409 displays potent antiproliferative properties in human tumor cell lines and antiangiogenic activity.

JNJ-10198409

Reference: SM62-5

€0.00 (tax incl.)

JNJ-10198409 displays potent antiproliferative properties in human tumor cell lines and antiangiogenic activity.

JNJ-10198409

Reference: SM62-50

€0.00 (tax incl.)

JNJ-10198409 displays potent antiproliferative properties in human tumor cell lines and antiangiogenic activity.

KY02111

Reference: SM64-2

€0.00 (tax incl.)

KY02111 promotes differentiation of human pluripotent stem cells (hPSC) to cardiomyocytes by inhibiting Wnt signaling in hPSC in a manner that is distinct from that of previously studied Wnt inhibitors. The...

KY02111

Reference: SM64-10

€0.00 (tax incl.)

KY02111 promotes differentiation of human pluripotent stem cells (hPSC) to cardiomyocytes by inhibiting Wnt signaling in hPSC in a manner that is distinct from that of previously studied Wnt inhibitors. The...

KY02111

Reference: SM64-50

€0.00 (tax incl.)

KY02111 promotes differentiation of human pluripotent stem cells (hPSC) to cardiomyocytes by inhibiting Wnt signaling in hPSC in a manner that is distinct from that of previously studied Wnt inhibitors. The...

LDN193189

Reference: SM23-1

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LDN193189

Reference: SM23-5

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LDN193189

Reference: SM23-10

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LDN193189

Reference: SM23-50

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LY294002

Reference: SM24-10

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.

LY294002

Reference: SM24-50

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.

LY294002

Reference: SM24-100

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.

LY294002

Reference: SM24-1000

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.