IM-12
IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
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                Reference: 
                
                                                        SM04-10
              
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