Reagents

5-Azacytidine

Reference: SM07-50

€0.00 (tax incl.)

5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (DNMT), forming covalent adducts with cellular DNMT1 depleting enzyme activity. This small molecule enhances differentiation to...

5-Azacytidine

Reference: SM07-200

€0.00 (tax incl.)

5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (DNMT), forming covalent adducts with cellular DNMT1 depleting enzyme activity. This small molecule enhances differentiation to...

A769662

Reference: SM08-2

€0.00 (tax incl.)

A769662 inhibits 3T3-L1 adipocyte differentiation and may be used to treat obesity. It also inhibited the function of the 26S proteasome via an AMPK-independent mechanism.

A769662

Reference: SM08-10

€0.00 (tax incl.)

A769662 inhibits 3T3-L1 adipocyte differentiation and may be used to treat obesity. It also inhibited the function of the 26S proteasome via an AMPK-independent mechanism.

A769662

Reference: SM08-50

€0.00 (tax incl.)

A769662 inhibits 3T3-L1 adipocyte differentiation and may be used to treat obesity. It also inhibited the function of the 26S proteasome via an AMPK-independent mechanism.

A769662

Reference: SM08-200

€0.00 (tax incl.)

A769662 inhibits 3T3-L1 adipocyte differentiation and may be used to treat obesity. It also inhibited the function of the 26S proteasome via an AMPK-independent mechanism.

ALK5 Inhibitor II

Reference: SM09-1

€0.00 (tax incl.)

ALK5 can replace Sox2 for generation of induced pluripotent stem cells (iPSC).

ALK5 Inhibitor II

Reference: SM09-5

€0.00 (tax incl.)

ALK5 can replace Sox2 for generation of induced pluripotent stem cells (iPSC).

ALK5 Inhibitor II

Reference: SM09-10

€0.00 (tax incl.)

ALK5 can replace Sox2 for generation of induced pluripotent stem cells (iPSC).

ALK5 Inhibitor II

Reference: SM09-25

€0.00 (tax incl.)

ALK5 can replace Sox2 for generation of induced pluripotent stem cells (iPSC).

ALK5 Inhibitor II

Reference: SM09-50

€0.00 (tax incl.)

ALK5 can replace Sox2 for generation of induced pluripotent stem cells (iPSC).

BI-D1870

Reference: SM10-1

€0.00 (tax incl.)

BI-D1870 induces apoptosis, although preferentially, in a p21-deficient background. BI-D1870 also induces a strong transcription and p53-independent accumulation of p21 protein and protects cells from gamma...

BI-D1870

Reference: SM10-5

€0.00 (tax incl.)

BI-D1870 induces apoptosis, although preferentially, in a p21-deficient background. BI-D1870 also induces a strong transcription and p53-independent accumulation of p21 protein and protects cells from gamma...

BI-D1870

Reference: SM10-10

€0.00 (tax incl.)

BI-D1870 induces apoptosis, although preferentially, in a p21-deficient background. BI-D1870 also induces a strong transcription and p53-independent accumulation of p21 protein and protects cells from gamma...

BIRB796

Reference: SM11-2

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BIRB796 has been used as part of the naive human stem cell (NSHM) medium to create naive state human cells.

BIRB796

Reference: SM11-10

€0.00 (tax incl.)

BIRB796 has been used as part of the naive human stem cell (NSHM) medium to create naive state human cells.

BIRB796

Reference: SM11-25

€0.00 (tax incl.)

BIRB796 has been used as part of the naive human stem cell (NSHM) medium to create naive state human cells.

BIRB796

Reference: SM11-50

€0.00 (tax incl.)

BIRB796 has been used as part of the naive human stem cell (NSHM) medium to create naive state human cells.

BIRB796

Reference: SM11-100

€0.00 (tax incl.)

BIRB796 has been used as part of the naive human stem cell (NSHM) medium to create naive state human cells.

BIX01294 Trihydrochloride Hydrate

Reference: SM12-2

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BIX01294 modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in-vitro.

BIX01294 Trihydrochloride Hydrate

Reference: SM12-10

€0.00 (tax incl.)

BIX01294 modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in-vitro.

BIX01294 Trihydrochloride Hydrate

Reference: SM12-50

€0.00 (tax incl.)

BIX01294 modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in-vitro.

CHIR99021

Reference: SM13-1

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CHIR99021 is widely used in definitive endoderm differentiation protocols.

CHIR99021

Reference: SM13-5

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CHIR99021 is widely used in definitive endoderm differentiation protocols.

CHIR99021

Reference: SM13-10

€0.00 (tax incl.)

CHIR99021 is widely used in definitive endoderm differentiation protocols.

CHIR99021

Reference: SM13-50

€0.00 (tax incl.)

CHIR99021 is widely used in definitive endoderm differentiation protocols.

Cyclosporin A

Reference: SM43-50

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Cyclosporin A inhibits phosphatase activity of calcineurin. This small molecule also inhibits formation and opening of the mitochondrial permeability transition pore (MPTP).

Cyclosporin A

Reference: SM43-1000

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Cyclosporin A inhibits phosphatase activity of calcineurin. This small molecule also inhibits formation and opening of the mitochondrial permeability transition pore (MPTP).

Cyclosporin A

Reference: SM43-5000

€0.00 (tax incl.)

Cyclosporin A inhibits phosphatase activity of calcineurin. This small molecule also inhibits formation and opening of the mitochondrial permeability transition pore (MPTP).

CYT387

Reference: SM44-2

€0.00 (tax incl.)

CYT387 inhibits the proliferation of parental Ba/F3 cells (Ba/F3-wt) stimulated by IL-3. Furthermore, CYT387 also causes the inhibition of cell proliferation in cell lines constitutively activated by JAK2 or MPL...

CYT387

Reference: SM44-10

€0.00 (tax incl.)

CYT387 inhibits the proliferation of parental Ba/F3 cells (Ba/F3-wt) stimulated by IL-3. Furthermore, CYT387 also causes the inhibition of cell proliferation in cell lines constitutively activated by JAK2 or MPL...

CYT387

Reference: SM44-50

€0.00 (tax incl.)

CYT387 inhibits the proliferation of parental Ba/F3 cells (Ba/F3-wt) stimulated by IL-3. Furthermore, CYT387 also causes the inhibition of cell proliferation in cell lines constitutively activated by JAK2 or MPL...

DAPT

Reference: SM15-2

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DAPT causes neural cells to commit to neuronal differentiation.

DAPT

Reference: SM15-10

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DAPT causes neural cells to commit to neuronal differentiation.

DAPT

Reference: SM15-50

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DAPT causes neural cells to commit to neuronal differentiation.

Dasatinib

Reference: SM45-20

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Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Dasatinib

Reference: SM45-100

€0.00 (tax incl.)

Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Dasatinib

Reference: SM45-500

€0.00 (tax incl.)

Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Dasatinib

Reference: SM45-1000

€0.00 (tax incl.)

Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Dasatinib

Reference: SM45-5000

€0.00 (tax incl.)

Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Decitabine

Reference: SM46-5

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-25

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-50

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-250

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-1000

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Dexamethasone

Reference: SM47-25

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Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dexamethasone

Reference: SM47-250

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Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dexamethasone

Reference: SM47-500

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Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dexamethasone

Reference: SM47-1000

€0.00 (tax incl.)

Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dorsomorphin Dihydrochloride

Reference: SM03-2

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Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-10

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-50

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-200

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Fasudil Hydrochloride

Reference: SM49-10

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-50

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-250

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-500

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-1000

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Forskolin

Reference: SM18-2

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-10

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-50

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-100

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-1000

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Garcinol

Reference: SM52-1

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Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

Garcinol

Reference: SM52-5

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Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

Garcinol

Reference: SM52-25

€0.00 (tax incl.)

Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

GDC-0449

Reference: SM54-5

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GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-25

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-50

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-200

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0941

Reference: SM19-2

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GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-10

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GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-25

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-50

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-200

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

Geldanamycin

Reference: SM55-2

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-10

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-25

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-50

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-250

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Go 6983

Reference: SM20-1

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

Go 6983

Reference: SM20-5

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

Go 6983

Reference: SM20-10

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

GSK429286A

Reference: SM21-2

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GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GSK429286A

Reference: SM21-10

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GSK429286A

Reference: SM21-50

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GX15-070

Reference: SM56-2

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-10

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-50

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-200

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

ID-8

Reference: SM01-1

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-5

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-50

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-100

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...