Quote 5-Azacytidine
5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (DNMT), forming covalent adducts with cellular DNMT1 depleting enzyme activity. This small molecule enhances differentiation to cardiomyocytes from human embryonic stem cells. 5-Azacytidine also increases reprogramming efficiency of mouse fibroblasts to pluripotent stem cells.
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Reference:
SM07-200
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