Category: Reagents

Reference: R1005-.1
€0.00 (tax incl.)
Better performance of firefly luciferase mRNA modified by ARCA, 5mCTP and ΨUTP, inhibiting RNA-mediated innate immune activation, stable and efficient expression efficiency, used as an experimental control.
Reference: R1005-1
€0.00 (tax incl.)
Better performance of firefly luciferase mRNA modified by ARCA, 5mCTP and ΨUTP, inhibiting RNA-mediated innate immune activation, stable and efficient expression efficiency, used as an experimental control.
Reference: R1005-5
€0.00 (tax incl.)
Better performance of firefly luciferase mRNA modified by ARCA, 5mCTP and ΨUTP, inhibiting RNA-mediated innate immune activation, stable and efficient expression efficiency, used as an experimental control.
Reference: R1007-.1
€0.00 (tax incl.)
New modification with better performance --- direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control to study transfection and expression in mammalian cells.
Reference: R1007-1
€0.00 (tax incl.)
New modification with better performance --- direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control to study transfection and expression in mammalian cells.
Reference: R1007-5
€0.00 (tax incl.)
New modification with better performance --- direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control to study transfection and expression in mammalian cells.
Reference: R1008-.1
€0.00 (tax incl.)
5-moUTP-modified mRNA with better performance, Cy3 tag, direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control and tool for determining mRNA delivery and localization.
Reference: R1008-1
€0.00 (tax incl.)
5-moUTP-modified mRNA with better performance, Cy3 tag, direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control and tool for determining mRNA delivery and localization.
Reference: R1008-5
€0.00 (tax incl.)
5-moUTP-modified mRNA with better performance, Cy3 tag, direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control and tool for determining mRNA delivery and localization.
Reference: R1009-.1
€0.00 (tax incl.)
5-moUTP-modified mRNA with better performance, Cy5 tag, direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control and tool for determining mRNA delivery and localization.
Reference: R1009-1
€0.00 (tax incl.)
5-moUTP-modified mRNA with better performance, Cy5 tag, direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control and tool for determining mRNA delivery and localization.
Reference: R1009-5
€0.00 (tax incl.)
5-moUTP-modified mRNA with better performance, Cy5 tag, direct-detection reporter mRNA that suppresses RNA-mediated innate immune activation, used as control and tool for determining mRNA delivery and localization.
Reference: R1010-.1
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, modified by 5-moUTP and Cy5-utp, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation
Reference: R1010-1
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, modified by 5-moUTP and Cy5-utp, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation
Reference: R1010-5
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, modified by 5-moUTP and Cy5-utp, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation
Reference: R1011-.1
€0.00 (tax incl.)
EGFP mRNA with Cap 1 structure, modified by 5-moUTP and Cy5-utp, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation
Reference: R1011-1
€0.00 (tax incl.)
EGFP mRNA with Cap 1 structure, modified by 5-moUTP and Cy5-utp, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation
Reference: R1011-5
€0.00 (tax incl.)
EGFP mRNA with Cap 1 structure, modified by 5-moUTP and Cy5-utp, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation
Reference: R1012-.1
€0.00 (tax incl.)
Better performance of firefly luciferase mRNA modified by ARCA and 5-moUTP, inhibiting RNA-mediated innate immune activation, stable and efficient expression efficiency, used as an experimental control.
Reference: R1012-1
€0.00 (tax incl.)
Better performance of firefly luciferase mRNA modified by ARCA and 5-moUTP, inhibiting RNA-mediated innate immune activation, stable and efficient expression efficiency, used as an experimental control.
Reference: R1012-5
€0.00 (tax incl.)
Better performance of firefly luciferase mRNA modified by ARCA and 5-moUTP, inhibiting RNA-mediated innate immune activation, stable and efficient expression efficiency, used as an experimental control.
Reference: R1013-.1
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, modified by 5-moUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1013-1
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, modified by 5-moUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1013-5
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, modified by 5-moUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1016-.1
€0.00 (tax incl.)
EGFP mRNA with Cap 1 structure, modified by 5-moUTP,providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1016-1
€0.00 (tax incl.)
EGFP mRNA with Cap 1 structure, modified by 5-moUTP,providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1016-5
€0.00 (tax incl.)
EGFP mRNA with Cap 1 structure, modified by 5-moUTP,providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1017-.1
€0.00 (tax incl.)
mCherry mRNA with Cap 1 structure, modified by 5mCTP/ψUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1017-1
€0.00 (tax incl.)
mCherry mRNA with Cap 1 structure, modified by 5mCTP/ψUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1017-5
€0.00 (tax incl.)
mCherry mRNA with Cap 1 structure, modified by 5mCTP/ψUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Reference: R1018-.1
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, providing higher transcription efficiency and enhanced stability.
Reference: R1018-1
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, providing higher transcription efficiency and enhanced stability.
Reference: R1018-5
€0.00 (tax incl.)
Firefly Luciferase mRNA with Cap 1 structure, providing higher transcription efficiency and enhanced stability.
Reference: R1001-.1
€0.00 (tax incl.)
Direct-detection reporter mRNA, used as control to study transfection and expression in mammalian cells.
Reference: R1001-1
€0.00 (tax incl.)
Direct-detection reporter mRNA, used as control to study transfection and expression in mammalian cells.
Reference: R1001-5
€0.00 (tax incl.)
Direct-detection reporter mRNA, used as control to study transfection and expression in mammalian cells.
Reference: R1020-.1
€0.00 (tax incl.)
Human erythropoietin (EPO) mRNA with Cap 1 structure, modified by ψUTP, providing higher transcription efficiency, and suppressing RNA-mediated innate immune activation.
Reference: R1020-1
€0.00 (tax incl.)
Human erythropoietin (EPO) mRNA with Cap 1 structure, modified by ψUTP, providing higher transcription efficiency, and suppressing RNA-mediated innate immune activation.
Reference: R1020-5
€0.00 (tax incl.)
Human erythropoietin (EPO) mRNA with Cap 1 structure, modified by ψUTP, providing higher transcription efficiency, and suppressing RNA-mediated innate immune activation.
Reference: 11899-2,5
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A fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme; targets cell walls of pathogens such as S. aureus in a mouse sepsis model...
Reference: 13135-2,5
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A cytotoxic alkaloid; inhibits the growth of K562 leukemia and SW1116 colon cancer cells (IC50s = 20 and 28 nM, respectively); induces apoptosis of K562 cells via upregulation of the Bax/Bcl-2 ratio, decreasing...
Reference: 15386-2,5
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A macrocyclic antibiotic that exhibits cytotoxic effects in cancer cell lines, inhibiting cell proliferation (IC50 = 221.3 nM in HL-60 cells); 1-4 μM inhibits oxidized LDL-induced accumulation of cholesteryl esters in...
Reference: 15500-2,5
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A natural antifungal phytotoxin that selectively and potently inhibits fungal Pkc1, which are central to cell wall integrity (IC50 = 25 nM for Candida Pkc1); potently inhibits MAPK-interacting kinases Mnk1 and Mnk2...
Reference: 15504-2,5
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A benzoquinone ansamycin antibiotic that acts as a cell-permeable inhibitor of non-receptor tyrosine kinases and Hsp90; inhibits Bcr-Abl with an IC50 value of 5 μM, a concentration that also effectively blocks Src,...
Reference: 17090-2,5
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A natural acyldepsipeptide that is effective against Gram-positive bacteria, including penicillin-resistant S. aureus; is also effective against many strains of anaerobic bacteria
Reference: 17092-2,5
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A depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain; effective against Gram-positive bacteria, including methicillin-resistant S....
Reference: 17093-2,5
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A macrocyclic peptide antibiotic that prevents the growth of Gram-positive bacteria without affecting that of Gram-negative bacteria
Reference: 17095-2,5
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A structurally unusual antibiotic that inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63...
Reference: 17453-2,5
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A minor component of avermectin broth, used broadly against nematodes, ticks, flies, and ants
Reference: 17456-2,5
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One of four major analogs in the enniatin complex that has been shown to moderately inhibit ACAT activity in rat liver microsomes (IC50 = 22 µM); demonstrates anthelmintic properties against N. brasiliensis, T....
Reference: 17774-2,5
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A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC50s = 10.2 and 15.5 µM in rat liver microsomes and Raji cells, respectively
Reference: 17775-2,5
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A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC50s = 17.5 and 2.8 µM in rat liver microsomes and Raji cells, respectively)
Reference: 17914-2,5
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An indolocarbazole antibiotic produced by S. aerocolonigenes ATCC39243 that weakly inhibits DNA topoisomerase I; cytotoxic to human lung adenocarcinoma, colon carcinoma, and nasopharyngeal carcinoma cell lines (IC50s...
Reference: 18770-2,5
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A fungal metabolite that inhibits cyclooxygenase, blocking both the conversion of AA to PGH2 and the conversion of PGH2 to PGE2 (IC50s = 40 and 9 µM, respectively); also inhibits the reverse transcriptase of avian...
Reference: 19433-2,5
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An antibiotic that inhibits complex III of the mitochondrial ETC, preventing electron transport between cytochromes b and c, which results in the production of superoxide and eventual cell death; inhibits Bcl-2 and...
Reference: 19437-2,5
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An isoprenoid antibiotic and antiviral that suppresses PMA-induced invasion in renal carcinoma cells (IC50 = ~10 µM) by inhibiting the expression of MMP-9; profoundly increases the expression of p53 by increasing...
Reference: 19439-2,5
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An inhibitor of FAS-II, blocking fatty acid synthesis in S. aureus and E. coli with IC50 values of 11.4 and 35.3 µg/ml, respectively; inhibits the growth of S. aureus and premeable E. coli strains with MICs ranging...
Reference: 19440-2,5
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An inhibitor of DGK (Ki = 3.1 µM) and DGAT (IC50 = 5.6 µM); reduces the concentration of phosphatidic acid in T cell lymphoma (IC50 = 3 µM); binds to human CCR5 chemokine receptors with an IC50 value of 11 µM
Reference: 19444-2,5
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A kibdelone whose mode of action and pharmacology have not been studied
Reference: 19445-2,5
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Inhibits PANC-1 cell survival in nutrient-deprived media at a 100-fold lower concentration than that required for cells maintained in nutrient-rich media
Reference: 19450-2,5
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An inhibitor of the PTPs that blocks phosphorylation of CD45 and VHR (IC50s = 54 and 2 µM, respectively) and arrests cell cycle progress at the G1/S transition; also inhibits heparanase (IC50 = 17 µM), an...
Reference: 20133-2,5
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An antibiotic that inhibits growth in various tumor cell lines (IC50s = 1-5 µM) by activating caspases 8 and 3
Reference: 20184-2,5
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A macrolide antibiotic that inhibits the mitochondrial F1FOATPase; inhibits K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cyctoxic to SW620 colon cancer cells with an IC50 value...
Reference: 20220-2,5
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A glycosylated derivative of trichostatin A that has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations...
Reference: 20584-2,5
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An antibiotic that is particularly cytotoxic against S. aureus, including the methicillin resistant 535 strain (MICs = 3.1-6.2 µg/ml)
Reference: 20586-2,5
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An antibiotic active against a broad spectrum of microorganisms in vitro including P. acnes (MIC = 0.86 µg/ml), B. subtilis (MIC Enterobacter sp. (MIC = 64 µg/ml), Trichophyton sp. (MIC = 17.5 µg/ml), and Microsporum...
Reference: 20692-2,5
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A fungal metabolite that inhibits acinar morphogenesis, cell migration, and invasion in a 3D-matrigel assay system designed to study tumor cell motility
Reference: 21766-2,5
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An Hsp90 inhibitor; disrupts Hsp90 and Cdc37 binding; inhibits cell proliferation in HER2+ breast cancer cells (IC50 = 12.9-61.5 µM, respectively); decreases the number of invasive cells in vitro; inhibits cell...
Reference: 21767-2,5
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A natural COX inhibitor; blocks conversion of arachidonic acid to PGH2 (IC50 = 10 µM); blocks conversion of PGH2 to PGE2 (IC50 = 40 µM); inhibits glucose-6-phosphatase (IC50 = 4.6 µM); non-competitively inhibits...
Reference: 21999-2,5
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A component of the antimycin A antibiotic complex; more polar than antimycins A1, A2, and A3; inhibits ATP-citrate lyase with a Ki value of 64.8 µM
Reference: 22001-2,5
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A cyclodepsipeptide insecticide; synthesized by B. bassiana and V. lecanii; induces atony in B. mori when given orally at concentrations as low as 4 ppm; inhibits the muscarinic, but not nicotinic, receptor-induced...
Reference: 22063-2,5
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A phthalide antibacterial agent; strong anti-H. pylori effect (MIC = 0.2 µg/cm3); 1-40 µM inhibits LoVo and HL-60 cell proliferation
Reference: 22066-2,5
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A depsipeptide antifungal; inhibits ERG synthesis (IC50 = 34 ng/ml); selectively inhibits growth of C. albicans (MIC = 32 µg/ml); acts synergistically with fluconazole to reduce growth of azole-resistant C. albicans...
Reference: 22068-2,5
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Reference: 22069-2,5
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A diketopiperazine metabolite from P. citreovirde; cytotoxic against HeLa cells at 8.4 μM
Reference: 22168-2,5
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An inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 µM) and P. falciparum FAS-II; cytotoxic to U87MG and KB cancerous cell lines (IC50s = 79.40 and 56.22 mg/L, respectively); active against Plasmodium species...
Reference: 22584-2,5
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A mycotoxin with antiviral activity; it inhibits HIV-1 protease in vitro (IC50 = 161 μM); no observable cytotoxicity at concentrations up to 100 μM in HepG2 cells,
Reference: 23140-2,5
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A pyrone isolated from S. pactum; selective and potent antimicrobial activity against H. pylori (MIC 0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa,...
Reference: 23149-2,5
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A hydroquinone ansamycin antibiotic; inhibits B. brevis and M. flavus (MICs = 50 and 25 μg/mL, respectively); inhibits lymphocytic leukemia cell lines P388 and KB (ED50s = 0.34 and 3.49 μg/mL, respectively)
Reference: 23240-2,5
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An aurodox antibiotic; has weak activity against S. pneumoniae PARK, S. pyogenes, and H. influenzae (MICs = 16, 32, and 64 μg/ml, respectively, in a broth dilutiion assay
Reference: 23477-2,5
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A bacterial metabolite with anticancer properties; inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 µM; has antibacterial activity against Gram-positive...
Reference: 23491-2,5
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A phenalenone that inhibits HIV-1 integrase (IC50 = 10 μM) and HIV-1 replication in human peripheral blood cells transformed by murine leukemia virus (HPB-M(a); IC50 = 1.7 μM); less cytotoxic to HPB-M(a) cells (IC50 =...
Reference: 23766-2,5
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A cysteine protease inhibitor (Kis = 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively); inhibits the growth of T. brucei in vitro (IC50 = 30.87 μM); cytotoxic to...
Reference: 23824-2,5
€0.00 (tax incl.)
The minor component (

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