Tetromycin B
A cysteine protease inhibitor (Kis = 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively); inhibits the growth of T. brucei in vitro (IC50 = 30.87 μM); cytotoxic to HEK293T kidney cells and J774.1 macrophages (IC50s = 71.77 and 20.2 μM, respectively)
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Reference:
23766-2,5
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