Ginsenoside Rb3 Reference: 29005-10 A steroid glycoside with diverse biological activities; inhibits OGD-induced JNK-mediated activation of NF-κB and apoptosis in H9c2 mouse cardiac myoblasts; reduces myocardial apoptosis and production of ROS in a rat model of myocardial ischemia-reperfusion injury at 20 mg/kg; prevents increases in serum creatinine, BUN, MDA, and decreases in SOD activity and GSH levels, as well as inhibits renal cell apoptosis in a mouse model of cisplatin-induced nephrotoxicity at 10 and 20 mg/kg; decreases the abundance of cancer cachexia-associated gut microbiota and the number of polyps in the ApcMin/+ mouse model of colon cancer; decreases immobility time in the forced swim and tail suspension tests in mice
Akt Inhibitor XI Reference: 18604-10 A cell-permeable, copper-containing 3-formylchromone derivative that inhibits Akt in an array of cancer cells (IC50s = 10-34 µM); also causes NF-κB inactivation in an orthotopic pancreatic tumor model using COLO 357 cells
Ginsenoside Rb3 Reference: 29005-100 A steroid glycoside with diverse biological activities; inhibits OGD-induced JNK-mediated activation of NF-κB and apoptosis in H9c2 mouse cardiac myoblasts; reduces myocardial apoptosis and production of ROS in a rat model of myocardial ischemia-reperfusion injury at 20 mg/kg; prevents increases in serum creatinine, BUN, MDA, and decreases in SOD activity and GSH levels, as well as inhibits renal cell apoptosis in a mouse model of cisplatin-induced nephrotoxicity at 10 and 20 mg/kg; decreases the abundance of cancer cachexia-associated gut microbiota and the number of polyps in the ApcMin/+ mouse model of colon cancer; decreases immobility time in the forced swim and tail suspension tests in mice
Akt Inhibitor XI Reference: 18604-25 A cell-permeable, copper-containing 3-formylchromone derivative that inhibits Akt in an array of cancer cells (IC50s = 10-34 µM); also causes NF-κB inactivation in an orthotopic pancreatic tumor model using COLO 357 cells
Ginsenoside Rb3 Reference: 29005-5 A steroid glycoside with diverse biological activities; inhibits OGD-induced JNK-mediated activation of NF-κB and apoptosis in H9c2 mouse cardiac myoblasts; reduces myocardial apoptosis and production of ROS in a rat model of myocardial ischemia-reperfusion injury at 20 mg/kg; prevents increases in serum creatinine, BUN, MDA, and decreases in SOD activity and GSH levels, as well as inhibits renal cell apoptosis in a mouse model of cisplatin-induced nephrotoxicity at 10 and 20 mg/kg; decreases the abundance of cancer cachexia-associated gut microbiota and the number of polyps in the ApcMin/+ mouse model of colon cancer; decreases immobility time in the forced swim and tail suspension tests in mice
Akt Inhibitor XI Reference: 18604-5 A cell-permeable, copper-containing 3-formylchromone derivative that inhibits Akt in an array of cancer cells (IC50s = 10-34 µM); also causes NF-κB inactivation in an orthotopic pancreatic tumor model using COLO 357 cells
Ginsenoside Rb3 Reference: 29005-50 A steroid glycoside with diverse biological activities; inhibits OGD-induced JNK-mediated activation of NF-κB and apoptosis in H9c2 mouse cardiac myoblasts; reduces myocardial apoptosis and production of ROS in a rat model of myocardial ischemia-reperfusion injury at 20 mg/kg; prevents increases in serum creatinine, BUN, MDA, and decreases in SOD activity and GSH levels, as well as inhibits renal cell apoptosis in a mouse model of cisplatin-induced nephrotoxicity at 10 and 20 mg/kg; decreases the abundance of cancer cachexia-associated gut microbiota and the number of polyps in the ApcMin/+ mouse model of colon cancer; decreases immobility time in the forced swim and tail suspension tests in mice
N-acetyl Tryptamine Reference: 18605-10 A structural analog of melatonin that binds the melatonin MT2 receptor (Ki = 41 nM); acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina