Reagents (2)

Dasatinib

Reference: SM45-1000

€0.00 (tax incl.)

Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Dasatinib

Reference: SM45-5000

€0.00 (tax incl.)

Dasatinib treatment inhibits SRC signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer stem cells.

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-25

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-50

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-250

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Decitabine

Reference: SM46-1000

€0.00 (tax incl.)

Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits DNA methyltransferase. DNA methylation has been noted to be important in...

Dexamethasone

Reference: SM47-25

€0.00 (tax incl.)

Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dexamethasone

Reference: SM47-250

€0.00 (tax incl.)

Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dexamethasone

Reference: SM47-500

€0.00 (tax incl.)

Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dexamethasone

Reference: SM47-1000

€0.00 (tax incl.)

Dexamethasone inhibits induction of nitric oxide synthase. Dexamethasone reduces levels of activated NF-kappaB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. This biomolecule induces...

Dorsomorphin Dihydrochloride

Reference: SM03-2

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-10

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-50

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Dorsomorphin Dihydrochloride

Reference: SM03-200

€0.00 (tax incl.)

Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Fasudil Hydrochloride

Reference: SM49-10

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-50

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-250

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-500

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Fasudil Hydrochloride

Reference: SM49-1000

€0.00 (tax incl.)

Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC)...

Forskolin

Reference: SM18-2

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-10

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-50

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-100

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Forskolin

Reference: SM18-1000

€0.00 (tax incl.)

Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced...

Garcinol

Reference: SM52-1

€0.00 (tax incl.)

Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

Garcinol

Reference: SM52-5

€0.00 (tax incl.)

Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

Garcinol

Reference: SM52-25

€0.00 (tax incl.)

Garcinol predominantly down-regulates global gene expression in HeLa cells. Additional research shows that Garcinol exhibits anti-carcinogenic and anti-inflammatory properties through selectively suppressing...

GDC-0449

Reference: SM54-5

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-25

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-50

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0449

Reference: SM54-200

€0.00 (tax incl.)

GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding...

GDC-0941

Reference: SM19-2

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-10

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-25

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-50

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

GDC-0941

Reference: SM19-200

€0.00 (tax incl.)

GDC-0941 plays a vital role in diverse cellular functions such as cell growth and proliferation. This small molecule is deregulated in a number of conditions, including cancer.

Geldanamycin

Reference: SM55-2

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-10

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-25

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-50

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Geldanamycin

Reference: SM55-250

€0.00 (tax incl.)

Geldanamycin has antiproliferative and antitumor effects, as it binds to HSP90, inhibits the HSP90-mediated conformational maturation/refolding reaction. It interferes with cellular stress response. Geldanamycin...

Go 6983

Reference: SM20-1

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

Go 6983

Reference: SM20-5

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

Go 6983

Reference: SM20-10

€0.00 (tax incl.)

Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic...

GSK429286A

Reference: SM21-2

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GSK429286A

Reference: SM21-10

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GSK429286A

Reference: SM21-50

€0.00 (tax incl.)

GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).

GX15-070

Reference: SM56-2

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-10

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-50

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

GX15-070

Reference: SM56-200

€0.00 (tax incl.)

GX15-070 enhances the antimyeloma activity induced by melphalan, dexamethasone, or bortezomib. GX15-070 potentiates TRAIL-mediated apoptosis by unsequestering Bak and Bim from Bcl-2/Bcl-xL or Mcl-1 proteins in PANC-1...

ID-8

Reference: SM01-1

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-5

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-50

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

ID-8

Reference: SM01-100

€0.00 (tax incl.)

ID-8 enables the long term expansion of embryonic stem cells (ESC). ESC treated with ID-8 in a serum-free medium were subsequently consistently differentiated into many cell types, including neurons, muscle cells and...

IM-12

Reference: SM04-2

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-10

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-25

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-100

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

IM-12

Reference: SM04-500

€0.00 (tax incl.)

IM-12 significantly increases beta-catenin levels. IM-12 leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells by activating Wnt pathway. IM-12 when combined with other small...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-5

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-25

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-100

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-250

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

Irinotecan Hydrochloride Trihydrate

Reference: SM61-1000

€0.00 (tax incl.)

As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the...

IWP-2

Reference: SM39-2

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

IWP-2

Reference: SM39-10

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

IWP-2

Reference: SM39-50

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

IWP-2

Reference: SM39-100

€0.00 (tax incl.)

IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem...

JNJ-10198409

Reference: SM62-1

€0.00 (tax incl.)

JNJ-10198409 displays potent antiproliferative properties in human tumor cell lines and antiangiogenic activity.

JNJ-10198409

Reference: SM62-5

€0.00 (tax incl.)

JNJ-10198409 displays potent antiproliferative properties in human tumor cell lines and antiangiogenic activity.

JNJ-10198409

Reference: SM62-50

€0.00 (tax incl.)

JNJ-10198409 displays potent antiproliferative properties in human tumor cell lines and antiangiogenic activity.

KY02111

Reference: SM64-2

€0.00 (tax incl.)

KY02111 promotes differentiation of human pluripotent stem cells (hPSC) to cardiomyocytes by inhibiting Wnt signaling in hPSC in a manner that is distinct from that of previously studied Wnt inhibitors. The...

KY02111

Reference: SM64-10

€0.00 (tax incl.)

KY02111 promotes differentiation of human pluripotent stem cells (hPSC) to cardiomyocytes by inhibiting Wnt signaling in hPSC in a manner that is distinct from that of previously studied Wnt inhibitors. The...

KY02111

Reference: SM64-50

€0.00 (tax incl.)

KY02111 promotes differentiation of human pluripotent stem cells (hPSC) to cardiomyocytes by inhibiting Wnt signaling in hPSC in a manner that is distinct from that of previously studied Wnt inhibitors. The...

LDN193189

Reference: SM23-1

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LDN193189

Reference: SM23-5

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LDN193189

Reference: SM23-10

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LDN193189

Reference: SM23-50

€0.00 (tax incl.)

LDN193189 inhibits ectopic ossification and it is a potential agent in the treatment of NSCLC lung tumors, showing significant in-vivo clinical utility. LDN193189 has been used to reduce ectopic ossification in a...

LY294002

Reference: SM24-10

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.

LY294002

Reference: SM24-50

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.

LY294002

Reference: SM24-100

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.

LY294002

Reference: SM24-1000

€0.00 (tax incl.)

LY294002 inhibits cell proliferation of choroidal melanoma OCM-1 cells. In mouse embryonic stem cells, LY294002 prevents self-renewal by inhibiting LIF2.