12-keto Lithocholic Acid Reference: 29547-5 A metabolite of DCA; fecal levels are elevated in rats fed a diet supplemented with cholic acid or DCA compared with rats fed a control diet or a diet supplemented with cholesterol, HDCA, or LCA; activates the human PXR (EC50 = 31.3 μM in a cell-based transactivation assay); levels are increased in duodenal bile from patients with type 2 diabetes
Mitotane Reference: 18651-250 An inhibitor of steroidogenesis that suppresses the growth of adrenocortical cells; blocks the expression of several genes that encode proteins involved in steroidogenesis and disrupts mitochondrial respiratory chain activity in human adrenocortical cells
12-keto Lithocholic Acid Reference: 29547-50 A metabolite of DCA; fecal levels are elevated in rats fed a diet supplemented with cholic acid or DCA compared with rats fed a control diet or a diet supplemented with cholesterol, HDCA, or LCA; activates the human PXR (EC50 = 31.3 μM in a cell-based transactivation assay); levels are increased in duodenal bile from patients with type 2 diabetes
Mitotane Reference: 18651-500 An inhibitor of steroidogenesis that suppresses the growth of adrenocortical cells; blocks the expression of several genes that encode proteins involved in steroidogenesis and disrupts mitochondrial respiratory chain activity in human adrenocortical cells
4,4'-Dimethoxyoctafluorobiphenyl Reference: 18652-1 A compound that has been used to investigate the relationship between intramolecular rotational dynamics and molecular and crystal structure using NMR spin-lattice relaxation experiments
4,4'-Dimethoxyoctafluorobiphenyl Reference: 18652-5 A compound that has been used to investigate the relationship between intramolecular rotational dynamics and molecular and crystal structure using NMR spin-lattice relaxation experiments