BAY-678 Reference: 18615-1 A selective, cell permeable inhibitor of human neutrophil elastase (IC50 = 20 nM in vitro); has a favorable pharmacokinetic profile and demonstrates efficacy in acute in vivo models, including protease-induced acute lung injury in mice
BAY-678 Reference: 18615-10 A selective, cell permeable inhibitor of human neutrophil elastase (IC50 = 20 nM in vitro); has a favorable pharmacokinetic profile and demonstrates efficacy in acute in vivo models, including protease-induced acute lung injury in mice
20(S)-Protopanaxatriol Reference: 29073-1 An active ginsenoside metabolite; cytotoxic to HL-60 cancer cells (IC50 = 16 µM); inhibits the proliferation of HUVECs (EC50 = 6.64 µg/ml); blocks LPS-induced increases in the protein levels of COX-2 and iNOS and decreases LPS-induced NF-κB activity in RAW 264.7 cells from 1-20 µM
BAY-678 Reference: 18615-5 A selective, cell permeable inhibitor of human neutrophil elastase (IC50 = 20 nM in vitro); has a favorable pharmacokinetic profile and demonstrates efficacy in acute in vivo models, including protease-induced acute lung injury in mice
20(S)-Protopanaxatriol Reference: 29073-10 An active ginsenoside metabolite; cytotoxic to HL-60 cancer cells (IC50 = 16 µM); inhibits the proliferation of HUVECs (EC50 = 6.64 µg/ml); blocks LPS-induced increases in the protein levels of COX-2 and iNOS and decreases LPS-induced NF-κB activity in RAW 264.7 cells from 1-20 µM
R-(-)-Phenylephrine (hydrochloride) Reference: 18619-100 An adrenergic α1A receptor agonist (Ki = 1.4 µM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 µM, respectively); frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents