YZ9 Reference: 15352-5 A potent inhibitor of the glycolysis enzyme PFKFB3, with an IC50 value of 183 nM in vitro; avidly competes with F6P at PFKFB3 (Ki = 94 nM); cell permeable, inhibiting the growth of HeLa cells with a GI50 value of 2.7 µM
YZ9 Reference: 15352-50 A potent inhibitor of the glycolysis enzyme PFKFB3, with an IC50 value of 183 nM in vitro; avidly competes with F6P at PFKFB3 (Ki = 94 nM); cell permeable, inhibiting the growth of HeLa cells with a GI50 value of 2.7 µM
RGDS Peptide Reference: 15359-10 A tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen; interacts with α5β1 and αVβ3 integrins, blocking the attachment of cells to fibronectin-coated surfaces (Ki = 0.6 mM); inhibits adhesion of platelets to fibronectin, fibrinogen α, and von Willebrand factor (IC50 = ~10 μM)
RGDS Peptide Reference: 15359-25 A tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen; interacts with α5β1 and αVβ3 integrins, blocking the attachment of cells to fibronectin-coated surfaces (Ki = 0.6 mM); inhibits adhesion of platelets to fibronectin, fibrinogen α, and von Willebrand factor (IC50 = ~10 μM)