EZ Cap™ Cas9 mRNA (5-moUTP) Reference: R1015-1 Used with guideRNA for site-specific DNA cleavage in genome editing.
(−)-Isopulegol Reference: 23161-100 A monoterpene with diverse biological activities; antibacterial activity against S. aureus, E. faecium, E. coli, and M. smegmatis (MICs = 0.78, 12.5, 0.78, and 1.56 μl/ml, respectively, in an agar diffusion assay) and antifungal activity against C. albicans and A. niger (MIC = 1.56 μl/ml for both in an agar diffusion assay); inhibits C. albicans morphogenesis, adhesion, and biofilm formation (MICs = 0.125, 4, and 0.25 mg/ml, respectively); increases immobility time in the forced swim and tail suspension tests and increases the number of head dips in a hole board test and time spent in the open arms of the elevated plus maze in mice at 50 mg/kg; reduces the size of ulcerated lesions in the stomach in mouse models of ethanol- and indomethacin-induced gastric lesions at 100 mg/kg,
4-oxo-2-Nonenal-d3 Reference: 10004174-100 4-ONE-d3 contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-ONE by GC- or LC-MS.
Herbimycin A Reference: 15504-2,5 A benzoquinone ansamycin antibiotic that acts as a cell-permeable inhibitor of non-receptor tyrosine kinases and Hsp90; inhibits Bcr-Abl with an IC50 value of 5 μM, a concentration that also effectively blocks Src, Yes, Fps, Ros, and ErbB; binds Hsp90 and destabilizes client proteins, including Src, Bcr-Abl, and ErbB2
EZ Cap™ Cas9 mRNA (5-moUTP) Reference: R1015-5 Used with guideRNA for site-specific DNA cleavage in genome editing.
(−)-Isopulegol Reference: 23161-25 A monoterpene with diverse biological activities; antibacterial activity against S. aureus, E. faecium, E. coli, and M. smegmatis (MICs = 0.78, 12.5, 0.78, and 1.56 μl/ml, respectively, in an agar diffusion assay) and antifungal activity against C. albicans and A. niger (MIC = 1.56 μl/ml for both in an agar diffusion assay); inhibits C. albicans morphogenesis, adhesion, and biofilm formation (MICs = 0.125, 4, and 0.25 mg/ml, respectively); increases immobility time in the forced swim and tail suspension tests and increases the number of head dips in a hole board test and time spent in the open arms of the elevated plus maze in mice at 50 mg/kg; reduces the size of ulcerated lesions in the stomach in mouse models of ethanol- and indomethacin-induced gastric lesions at 100 mg/kg,