Category: Proteins & Peptides

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Reference: HY-P3669

Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates.

Reference: GTX00443-pro

This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 9 (HSP9), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 216]

Reference: HY-P1267

α-Conotoxin PnIA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease.

Reference: GTX00444-pro

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 216]

Reference: GTX00445-pro

STIP1 is an adaptor protein that coordinates the functions of HSP7 (see HSPA1A; MIM 1455) and HSP9 (see HSP9AA1; MIM 14571) in protein folding. It is thought to assist in the transfer of proteins from HSP7 to HSP9 by binding both HSP9 and substrate-bound HSP7. STIP1 also stimulates the ATPase activity of HSP7 and inhibits the ATPase activity of HSP9, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 25 [PubMed 161115]).[supplied by OMIM, Jul 29]

Reference: HY-P1146

MEHFPGP (Semax) is a nootropic neuroprotective peptide. MEHFPGP can be used in the research of brain stroke.

Reference: GTX00446-pro

This intronless gene encodes a 7kDa heat shock protein which is a member of the heat shock protein 7 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 28]

Reference: HY-P0267

Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.

Reference: GTX00447-pro

This intronless gene encodes a 7kDa heat shock protein which is a member of the heat shock protein 7 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 28]

Reference: HY-W010830

Fmoc-Lys(Tfa)-OH is a lysine derivative.

Reference: GTX00448-pro

This intronless gene encodes a 7kDa heat shock protein which is a member of the heat shock protein 7 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 28]