Category: Proteins & Peptides

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MKRN3 blocking peptide

Reference: GTX32153-PEP

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 28]

ARG1 (human, recombinant)

Reference: 32558-50

Source: Active recombinant human C-terminal His-tagged ARG1 expressed in HEK293 cells • Amino acids: 1-322 (full length) • MW: 36 kDa

RSPO3 blocking peptide

Reference: GTX32155-PEP

This gene encodes a member of the thrombospondin type 1 repeat supergene family. In addition, the protein contains a furin-like cysteine-rich region. Furin-like repeat domains have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases. [provided by RefSeq, Jul 28]

COX-1 (ovine) Electrophoresis Standard

Reference: 360100-1

To be used as a standard for WB and electrophoresis. This enzyme has been carefully purified to exclude all unrelated proteins; may not be catalytically active. • COX-1 catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2.

COX-2 (ovine) Electrophoresis Standard

Reference: 360120-1

Cyclooxygenase catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of cyclooxygenase by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of cyclooxygenase, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions.(4,3622) COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep.(2,7,2884,4051)

ADAM29 blocking peptide

Reference: GTX32157-PEP

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 28]

iNOS Electrophoresis Standard

Reference: 360862-1

Each vial contains 5 µg of iNOS (murine macrophage) to be used as a standard for WB and electrophoresis. The enzyme has been carefully purified to exclude all unrelated proteins; may not be catalytically active.

PACS1 blocking peptide

Reference: GTX32158-PEP

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 28]

nNOS Electrophoresis Standard

Reference: 360870-1

Each vial contains nNOS (rat) to be used as a standard for WB and electrophoresis. The enzyme has been carefully purified to exclude all unrelated proteins; may not be catalytically active.(1281)

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