Quote Recombinant Newcastle disease virus Hemagglutinin-neuraminidase(HN),partial
Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
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Reference:
CSB-EP336075NCW1_100
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