PVR/CD155 Extracellular Domain (human, recombinant) Reference: 31826-50 Source: Active recombinant C-terminal human IgG1 Fc-tagged PVR expressed in HEK293 cells • Amino acids: 21-343 • MW: 61.8 kDa
FcγRIIIb/CD16b HNA-1b allotype (human, recombinant) Reference: 31827-20 Source: Recombinant human FcγRIIIb expressed in E. coli • Amino acids: 18-193 • MW: 20 kDa
CCR7 blocking peptide Reference: GTX31906-PEP The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 214]
FcγRIIIb/CD16b HNA-1b allotype (human, recombinant) Reference: 31827-50 Source: Recombinant human FcγRIIIb expressed in E. coli • Amino acids: 18-193 • MW: 20 kDa
TNFRSF7/CD27 Extracellular Domain (human, recombinant) Reference: 31828-100 Source: Active recombinant C-terminal human IgG1 Fc-His-tagged CD27 expressed in HEK293 cells • Amino acids: 21-192 • MW: 47.2 kDa
ARF6 blocking peptide Reference: GTX31908-PEP This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 28]
TNFRSF7/CD27 Extracellular Domain (human, recombinant) Reference: 31828-200 Source: Active recombinant C-terminal human IgG1 Fc-His-tagged CD27 expressed in HEK293 cells • Amino acids: 21-192 • MW: 47.2 kDa
SUZ12 blocking peptide Reference: GTX31909-PEP This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 29]
TNFRSF8/CD30 Long Isoform (human, recombinant) Reference: 31829-100 Source: Active recombinant C-terminal human IgG1 Fc-His-tagged CD30 expressed in HEK293 cells • Amino acids: 19-379 • MW: 66.5 kDa
PGC1 alpha blocking peptide Reference: GTX31910-PEP The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 28]