Soluble BLyS/BAFF (human, recombinant) Reference: 31824-100 Source: Active recombinant N-terminal human IgG1 Fc-tagged BLyS/BAFF expressed in HEK293 cells • Amino acids: 134-285 • MW: 43.7 kDa
LC3B blocking peptide Reference: GTX31899-PEP The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 28]
Soluble BLyS/BAFF (human, recombinant) Reference: 31824-20 Source: Active recombinant N-terminal human IgG1 Fc-tagged BLyS/BAFF expressed in HEK293 cells • Amino acids: 134-285 • MW: 43.7 kDa
SDF1 blocking peptide Reference: GTX31900-PEP This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 21]
Soluble BLyS/BAFF (human, recombinant) Reference: 31824-5 Source: Active recombinant N-terminal human IgG1 Fc-tagged BLyS/BAFF expressed in HEK293 cells • Amino acids: 134-285 • MW: 43.7 kDa
DRP1 blocking peptide Reference: GTX31901-PEP The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 28]
4-1BB/CD137 Extracellular Domain (human, recombinant) Reference: 31825-100 Source: Recombinant C-terminal human IgG1 Fc-His-tagged 4-1BB expressed in HEK293 cells • Amino acids: 25-186 • MW: 45.2 kDa
RPSA blocking peptide Reference: GTX31902-PEP Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p4 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 28]
4-1BB/CD137 Extracellular Domain (human, recombinant) Reference: 31825-200 Source: Recombinant C-terminal human IgG1 Fc-His-tagged 4-1BB expressed in HEK293 cells • Amino acids: 25-186 • MW: 45.2 kDa
THAP11 blocking peptide Reference: GTX31903-PEP The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 28]
PVR/CD155 Extracellular Domain (human, recombinant) Reference: 31826-100 Source: Active recombinant C-terminal human IgG1 Fc-tagged PVR expressed in HEK293 cells • Amino acids: 21-343 • MW: 61.8 kDa
Aquaporin 2 blocking peptide Reference: GTX31904-PEP This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 28]