Category: Proteins & Peptides

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IL28B blocking peptide

Reference: GTX31893-PEP

This gene encodes a cytokine distantly related to type I interferons and the IL-1 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 1 receptor, beta (IL1RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 28]

IL9 blocking peptide

Reference: GTX31894-PEP

The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 28]

AIMP2 blocking peptide

Reference: GTX31896-PEP

The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 2 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown. [provided by RefSeq, Jul 28]

B7-H4 (human, recombinant)

Reference: 31823-100

Source: Active recombinant C-terminal human IgG1 Fc-tagged B7-H4 expressed in HEK293 cells • Amino acids: 29-258 • MW: 52.3 kDa

B7-H4 (human, recombinant)

Reference: 31823-50

Source: Active recombinant C-terminal human IgG1 Fc-tagged B7-H4 expressed in HEK293 cells • Amino acids: 29-258 • MW: 52.3 kDa

LC3A blocking peptide

Reference: GTX31898-PEP

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 212]

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