PD-1 Extracellular Domain (human, recombinant) Reference: 28377-100 Source: Recombinant C-terminal human IgG1 Fc-His-tagged PD-1 expressed in HEK293 cells • Amino acids: 1-167 • MW: 44 kDa
PD-1 Extracellular Domain (human, recombinant) Reference: 28377-50 Source: Recombinant C-terminal human IgG1 Fc-His-tagged PD-1 expressed in HEK293 cells • Amino acids: 1-167 • MW: 44 kDa
SIPA1 blocking peptide Reference: GTX31846-PEP The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 28]
PD-L1 Extracellular Domain (human, recombinant) Reference: 28378-100 Source: Recombinant C-terminal mouse IgG1 Fc-tagged human PD-L1 expressed in HEK293 cells • Amino acids: 19-239 • MW: 51.7 kDa
NKX2.1 blocking peptide Reference: GTX31847-PEP This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 211]
PD-L1 Extracellular Domain (human, recombinant) Reference: 28378-20 Source: Recombinant C-terminal mouse IgG1 Fc-tagged human PD-L1 expressed in HEK293 cells • Amino acids: 19-239 • MW: 51.7 kDa
PD-L2 Extracellular Domain (human, recombinant) Reference: 28379-100 Source: Active recombinant human C-terminal His-tagged PD-L2 expressed in HEK293 cells • Amino acids: 20 -219 • MW: 24 kDa
ZFX blocking peptide Reference: GTX31851-PEP This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 21]
PD-L2 Extracellular Domain (human, recombinant) Reference: 28379-200 Source: Active recombinant human C-terminal His-tagged PD-L2 expressed in HEK293 cells • Amino acids: 20 -219 • MW: 24 kDa
ERR beta blocking peptide Reference: GTX31852-PEP This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. [provided by RefSeq, Jul 28]