Category: Proteins & Peptides

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Reference: 20594-100

Source: Recombinant N-terminal GST-tagged annexin V expressed in E. coli • Amino acids: 2-320 (full length) • MW: 62.4 kDa

Reference: GTX31814-PEP

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. [provided by RefSeq, Jul 28]

Reference: 20631-125

Source: Active recombinant N-terminal His-tagged enzyme isolated from a HEK293 overexpression system • MW: 71 kDa (~16 & 63 kDa purified) • PCSK9 is a member of the subtilisin serine protease family with an important role in lipoprotein metabolism. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in LDL cholesterol levels.

Reference: 20631-50

Source: Active recombinant N-terminal His-tagged enzyme isolated from a HEK293 overexpression system • MW: 71 kDa (~16 & 63 kDa purified) • PCSK9 is a member of the subtilisin serine protease family with an important role in lipoprotein metabolism. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in LDL cholesterol levels.

Reference: GTX31816-PEP

PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 23 [PubMed 1296857]).[supplied by OMIM, Mar 28]

Reference: GTX31818-PEP

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 23 [PubMed 12659941]).[supplied by OMIM, Aug 28]

Reference: GTX31819-PEP

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 28]