Carbamylated Human Fibrinogen Reference: 21370-1 Source: Fibrinogen purified from human plasma and modified with potassium cyanate • MW: α chain isoform 1 (95 kDa), α chain isoform 2 (69.8 kDa), β chain (55.9 kDa), and isoform γ-B chain (51.5 kDa) ,
HO-1 (human, recombinant) Reference: 22731-50 Source: C-terminal histidine-tagged HO-1 recombinant human protein expressed in E. coli • Amino acids: 1-265 (full length) • MW: 31 kDa
ZNF198 blocking peptide Reference: GTX31821-PEP The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 21]
cGAS (161-522) (human recombinant) Reference: 25001-100 Source: N-terminal His-tagged human cGAS protein (truncated), purified from E. coli • Amino acids: 161-522 • MW: 44.6 kDa
Axin 2 blocking peptide Reference: GTX31822-PEP The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 28]
Citrullinated GRP78 (human recombinant) Reference: 25107-100 Source: N-Terminal His-tagged human GRP78 purified from E. coli, citrullinated by PAD2 • MW: 74.6 kDa
Citrullinated Hsp70 (human recombinant) Reference: 25108-100 Source: N-Terminal histidine-tagged human Hsp70 purified from E. coli, citrullinated by PAD2 • MW: 71.7 kDa,
RIG-I helicase domain (human, recombinant) Reference: 25620-50 Source: Recombinant N-terminal histidine-tagged RIG-I helicase domain purified from E. coli • Amino acids: 232-794 • MW: 66.47 kDa
ESRP1 blocking peptide Reference: GTX31825-PEP ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 29 [PubMed 19285943]).[supplied by OMIM, Aug 29]