HDAC9 (human, recombinant) Reference: 10009466-1 Source: 5 µg of recombinant C-terminal His-tagged protein expressed in baculovirus expression system · MW: 50.7 kDa • HDAC9 is a Class IIa HDAC that can shuttle between the nucleus and cytoplasm, suggesting possible extranuclear functions including regulating the acetylation status of non-histone substrates.
BAMBI blocking peptide Reference: GTX31590-PEP This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 28]
FABP1 (human, recombinant) Reference: 10009547-100 Source: Recombinant N-terminal hexahistidine-tagged protein expressed in E. coli • Mr: 18.3 kDa
LIN54 blocking peptide Reference: GTX31591-PEP LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes (Schmit et al., 29 [PubMed 19725879]).[supplied by OMIM, Dec 21]
FABP2 (human recombinant) Reference: 10009548-100 Source: recombinant N-terminal His-tagged protein expressed in E. coli • Mr: 19.3 kDa
FABP4 (human, recombinant) Reference: 10009549-100 Source: Recombinant N-terminal His-tagged protein expressed in E. coli · Mr: 18.8 kDa
FABP7 (human, recombinant) Reference: 10009551-100 Source: Recombinant N-terminal His-tagged protein expressed in E. coli · MW: 19.1 kDa
Vezatin blocking peptide Reference: GTX31594-PEP This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 211]
sPLA2 (human recombinant Type V) Reference: 10009563-25 Source: Recombinant protein expressed in E. coli · MW: 13.72 kDa • PLA2 (Type V) is a secretory PLA2 (sPLA2) that catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids. It is responsible for arachidonic acid mobilization leading to prostaglandin production in macrophages and mast cells.
AKAP 82 blocking peptide Reference: GTX31595-PEP The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 28]