Prostaglandin D Synthase (lipocalin-type, human recombinant) Reference: 10006788-250 Source: Recombinant N-terminal GST-tagged enzyme purified from E. coli • MW: 46 kDa
FABP3 (human, recombinant) Reference: 10007432-100 Source: Recombinant protein N-terminal His-tag expressed in E. coli · Mr: 19 kDa · Protein concentration: 0.5 mg/ml
FABP5 (mouse recombinant) Reference: 10007433-100 Source: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli · Mr: 19.3 kDa · Protein concentration: 0.5 mg/ml
PPARδ (human recombinant) Reference: 10007451-25 Source: recombinant protein expressed in Sf21 cells · Mr: 54 kDa • PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. PPARδ is a mediator of diverse physiological functions including lipid and cholesterol homeostasis, embryo implantation, and cancer development. Most recently, attention has been focused on the role of PPARδ in obesity.
Calcium Sensing Receptor blocking peptide Reference: GTX31574-PEP The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 28]
PPARδ (human recombinant) Reference: 10007451-50 Source: recombinant protein expressed in Sf21 cells · Mr: 54 kDa • PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. PPARδ is a mediator of diverse physiological functions including lipid and cholesterol homeostasis, embryo implantation, and cancer development. Most recently, attention has been focused on the role of PPARδ in obesity.
Prorenin (human, recombinant) Reference: 10007599-100 Source: recombinant enzyme expressed in HEK cells · MW: 45 kDa
FKBP12 blocking peptide Reference: GTX31576-PEP The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK56 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 28]