Flamma® 648 ADIBO

Flamma® Fluors 648 ADIBO is a strain-promoted azide-alkyne cycloaddition (SPAAC) reagent of far-red dye induced from cyanine structure and used to generate a stable fluorescence signal in bioimaging. The maxima of Ex/Em values are at 649/666 nm, similar to that of Alexa 647, Cy5 and DyLight 650. Flamma 648 might be excited using 593 or 633 nm laser lines and displays excellent optical property. Flamma 648 ADIBO couples with an azide to form 1,4-disubstituted 1,2,3-triazole inside of living systems without using any coupling reagents or catalyst nor interfering native biochemical processes. Prior to perform SPAAC, the azide functionality should be introduced onto counterpart biomolecule by means of chemical or genetic modification. We offer Flamma Fluors 648 ADIBO as a click chemistry reagent dye for cellular imaging and nucleotide functionalization.