Flamma® 749 Carboxylic acid

Flamma® Fluors 749 Carboxylic acid is inactive form of near infrared (NIR) fluorescent dye induced from cyanine structure and used to generate a stable fluorescence signal in bioimaging. Flamma 749 fluorophore is attached with the hexanoic acid. The maxima of Ex/Em values are at 749/774 nm, similar to that of Alexa 750, Cy7, IRDye 750 and DyLight 755. Flamma 749 might be excited using 750 nm laser line or dye-pumped laser excitation and the emission occurs at biological tissue permeable NIR region. Flamma 749 acid might be coupled with primary amine at small molecules or on biomolecules by standard amide bond coupling conditions, or it might be converted to a reactive amine form by using standard chemical techniques. Flamma® Fluors 749 acid can be utilized as a reference standard for dye-conjugates.