Flamma® 648 Sulfo-NHS ester

Flamma® Fluors 648 Sulfo-NHS ester is a reactive form of far-red fluorescent dye induced from cyanine structure and used to generate a stable fluorescence signal in bioimaging. The maxima of Ex/Em values are at 648/663 nm, similar to that of Alexa 647, Cy 5, ATTO 647N and DyLight 650. Flamma 648 might be excited using 593 or 633 nm laser lines and displays excellent optical property. Flamma 648 can be conjugated to low-abundance biomolecules with great sensitivity and high molar ratios, allowing sensitive detection. Sulfo-NHS esters have higher water solubility than NHS esters, thus they do not need organic co-solvent and readily react with amine-modified oligonucleotides or amino groups of proteins, i.e. the ε-amino groups of lysine or the amine terminus of nucleotides to form a stable amide bond between dye and the biomolecule. We offer Flamma Fluors 648 Sulfo-NHS ester for labeling of antibodies, peptides, proteins, ligands, and amplification substrates optimized for cellular labeling and detection.