Flamma® 496 Vinylsulfone

Flamma® Fluors 496 Vinylsulfone is pH insensitive reactive form of bright green dye that used to generate a stable fluorescence signal in bioimaging. Vinylsulfone reactive group, developed by BioActs’ leading technology, is stable in a wide range of pH and at the high temperature. The maxima of Ex/Em values are at 496/520 nm, similar to that of Alexa 488. Flamma 496 might be excited using 488 nm laser line and displays excellent optical property. Flamma 496 can be conjugated to low-abundance of biomolecules with great sensitivity and high d/P ratio, enabling sensitive detection. Vinylsulfones readily react with primary amines of amino-modified oligonucleotides or of proteins to form a stable amino linkage between dye and the biomolecule. We offer Flamma 496 Vinylsulfone for labeling of antibodies, peptides, proteins, ligands and amplification substrates optimized for cellular labeling and detection.