Quote 9(S),12(S),13(S)-TriHOME
An oxylipin with diverse biological activities; has been found in various plants; is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner; inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50 = 28.7 µg/ml); inhibits LPS-induced NO production in BV-2 microglia (IC50 = 40.95 µM); enhances the antiviral IgA and IgG antibody responses induced by a nasal influenza HA vaccine in mice at 1g/animal
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Reference:
10005143-100
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