Quote Pseurotin A
Antibiotic. Chitin synthase, monoamine oxidase and IgE production inhibitor. Cytotoxic. Shows nematicidal and antileishmanial activity. Antiproliferative against four different glioma cells. Downregulates the expression of tumour glycolytic enzymes pyruvate kinase M2 (PKM2) and lactate dehydrogenase 5 (LDH5) and upregulates the expression of pyruvate dehydrogenase beta (PDHB), adenosine triphosphate synthase beta (ATPB) and cytochrome C, important regulators for tricarboxylic acid cycle and oxidative phosphorylation.
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Reference:
BVT-0003-M001
Brand: