Quote PD 166326
A pyridopyrimidine-type inhibitor of receptor tyrosine kinases that inhibits c-abl (IC50 = 8 nM) and Bcr/Abl-dependent cell growth (IC50 = 0.4 nM); also potently inhibits c-src (IC50 = 6 nM); effectively blocks Bcr/Abl kinase activity in vivo
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Reference:
9000988-10
Brand: