Quote Lapachol
A naphthoquinone with diverse biological activities; larvicidal against T. canis at 2 mg/ml; inhibits topoisomerase I and topoisomerase II activities, as well as induces apoptosis and DNA damage in C6 rat glioma cells at 10 and 100 µM; reduces B. atrox venom PLA2 activity in a turbidimetric assay at 10 µg/ml; reduces synovial leukocyte infiltration and joint destruction in a mouse model of collagen-induced arthritis at 3 and 10 mg/kg; reduces carrageenan-induced paw edema and abscess formation in rats
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Reference:
30190-100
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