1,10-Phenanthroline

1,10-Phenanthroline is a heterocyclic organic compound, which forms complexes with metal ions. It is a versatile ligand employed in the spectrophotometric determination of metals and photocatalytic reduction of carbon dioxide. The complexes that are build have wide applications in biochemistry, catalysis and analytical chemistry. 1,10-Phenanthroline is a ligand used in a mild, copper (II)-catalyzed cross-coupling of organoboronic acids and sulfinate salts leading to aryl- and alkenylsulfones. It is a conventional chelator to study its efficacy in Fenton's reaction-luminol chemiluminescence system. 1,10-Phenanthroline enhances hPSC differentiation into cranial placode cells and is known as a non-specific matrix metalloproteinase (MMP) inhibitor. 1,10-Phenanthroline is also used as a building block for metallomacrocycles and other biological active compounds, such as anti-cancer agents.