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List of products by brand PTM Bio
Reference: PTM-7454
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TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration
with TFIIB.
Reference: PTM-7455
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Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by
recruiting epigenetic chromatin modifiers. Plays a key role in gene...
Reference: PTM-7456
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TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration
with TFIIB.
Reference: PTM-7458
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Background Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC
oncogenic activities. Also interacts with MXD1-MAX heterodimers to...
Reference: PTM-7460
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This is a nuclear hormone receptor, serving as a transcription factor that facilitates the effects of vitamin D3 by regulating the expression of hormone-sensitive genes. It controls the transcription of these genes by...
Reference: PTM-7468
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Eukaryotic initiation factor 4A (eIF4A) has an essential role in the binding of mRNA to the 43S preinitiation complex when protein synthesis
begins, as eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs...
Reference: PTM-7469
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Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA
replication initiation and elongation in eukaryotic cells. Core component of...
Reference: PTM-7470
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Retinoblastoma-associated proteins 46 and 48 (RBAP46 and RBAP48, also known as RBBP7 and RBBP4), were first identified in human
cells as proteins that bind to retinoblastoma (Rb) tumor suppressor proteins. Since then,...
Reference: PTM-7471
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NELF-B is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA
polymerase II. The NELF complex causes transcriptional pausing and is counteracted by...
Reference: PTM-7472
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Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).
Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic...
Reference: PTM-7473
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CSDE1 is a highly conserved RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding
proteins in the cytoplasmic deadenylation/translational and decay interplay of the...
Reference: PTM-7475
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PARP2, also named as ADPRT2 and ADPRTL2, is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADPribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and...
Reference: PTM-7476
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As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form
during DNA replication or upon DNA stress. It prevents their reannealing and in...