Anti-Vitamin D3 Receptor Rabbit mAb
This is a nuclear hormone receptor, serving as a transcription factor that facilitates the effects of vitamin D3 by regulating the expression of hormone-sensitive genes. It controls the transcription of these genes by interacting with the WINAC complex, which is responsible for chromatin remodeling. It is recruited to promoters through its interaction with the WINAC complex subunit BAZ1B/WSTF, which facilitates the association with acetylated histones, a crucial step for the interaction between the receptor and the promoter region. Additionally, it plays a key role in maintaining calcium homeostasis
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Reference:
PTM-7460
Brand:
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