Category: Antibodies

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Reference: GTX16498
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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane...
Reference: GTX16500
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The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and...
Reference: GTX16516
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The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein...
Reference: GTX16517
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The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase...
Reference: GTX16544
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The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human...
Reference: GTX16545
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Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine...
Reference: GTX16546
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The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding...
Reference: GTX16550
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The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary...
Reference: GTX16551
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This gene is a member of the AB hydrolase superfamily and encodes a protein with an alpha/beta hydrolase fold. This domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origins and...
Reference: GTX16556
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The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to...
Reference: GTX16561
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The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 28]
Reference: GTX16562
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This gene encodes a mitochondrial acyl-coenzyme A synthetase that is specific for medium chain fatty acids. These enzymes catalyze fatty acid activation, the first step of fatty acid metabolism, through the transfer...
Reference: GTX16565
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This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively...
Reference: GTX16566
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This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic...
Reference: GTX16567
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided...
Reference: GTX16570
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Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells,...
Reference: GTX16571
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The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in...
Reference: GTX16573
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ERK (extracellular signal regulated kinase), also known as MAPK (mitogen-activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, respectively. These kinases belong to a family of...
Reference: GTX16574
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Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. it is...
Reference: GTX16575
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The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the...
Reference: GTX16576
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TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion...
Reference: GTX16577
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Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene...
Reference: GTX16578
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The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of...
Reference: GTX16579
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mouse homolog associates with peripheral-type benzodiazepine receptor and the regulatory subunit RIalpha of PKA [RGD, Feb 26]
Reference: GTX16580
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The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is...
Reference: GTX16583
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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC...
Reference: GTX16585
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This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of...
Reference: GTX16586
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This gene encodes a member of the non-ribosome peptide syntesase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4phosphate-binding) domain and...
Reference: GTX16588
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The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to...
Reference: GTX16592
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The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other...
Reference: GTX16597
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The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and...
Reference: GTX16598
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Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by...
Reference: GTX16602
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subunit of an L-type calcium channel that may be involved in bone metabolism and compensatory renal growth [RGD, Feb 26]
Reference: GTX16604
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low voltage-activated calcium channel subunit; important for calcium ion transport into nerve, muscle and endocrine cells [RGD, Feb 26]
Reference: GTX16608
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This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24...
Reference: GTX16609
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ion channel that demonstrates heat-evoked membrane currents [RGD, Feb 26]
Reference: GTX16610
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ion channel that may be activated by high temperature; may transduce high threshold heat responses in sensory ganglia [RGD, Feb 26]
Reference: GTX16612
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The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded...
Reference: GTX16618
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auxillary subinit of the voltage dependent calcium channel; may be involved in calcium current in the heart [RGD, Feb 26]
Reference: GTX16620
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may act as a regulatory component of a neuronal calcium channel [RGD, Feb 26]
Reference: GTX16621
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member of a family of gamma subunits of voltage-dependent calcium channels [RGD, Feb 26]
Reference: GTX16625
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member of a family of gamma subunits of voltage-dependent calcium channels [RGD, Feb 26]
Reference: GTX16626
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member of a family of gamma subunits of voltage-dependent calcium channels [RGD, Feb 26]
Reference: GTX16627
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forms a receptor regulated cation channel; mediates calcium transport in response to histamine H1 receptor activation [RGD, Feb 26]
Reference: GTX16629
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a G-protein-coupled receptor regulated Ca(2+) channel [RGD, Feb 26]
Reference: GTX16630
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a cation-selective channel; activated in response to systemic osmotic pressure [RGD, Feb 26]
Reference: GTX16633
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has high voltage L-type calcium channel activity that is sensitive to dihydropyridines [RGD, Feb 26]
Reference: GTX16634
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skeletal isoform and subunit of voltage dependent L-type Ca+2 channel; may mediate renal Ca+2 reabsorption; may play a role in bone metabolism [RGD, Feb 26]
Reference: GTX16635
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acts as an outwardly rectifying chloride channel; plays a role in chloride transport [RGD, Feb 26]
Reference: GTX16637
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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate,...
Reference: GTX16638
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voltage-gated potassium channel [RGD, Feb 26]
Reference: GTX16639
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a voltage-gated K+ channel; functions as a delayed rectifier-type K+ channel activated by large membrane depolarizations [RGD, Feb 26]
Reference: GTX16640
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voltage gated potassium channel; involved in the excitability in nerve and muscle [RGD, Feb 26]
Reference: GTX16641
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voltage gated potassium channel; functions as a delayed rectifier K+ channel [RGD, Feb 26]
Reference: GTX16642
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter...
Reference: GTX16644
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inwardly-rectifying potassium channel [RGD, Feb 26]
Reference: GTX16645
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MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits:...
Reference: GTX16646
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modulatory subunit of the MaxiK large conductance potassium channel; voltage and calcium-sensitive potassium channel [RGD, Feb 26]
Reference: GTX16647
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This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting...
Reference: GTX16648
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G-protein activated potassium channel [RGD, Feb 26]
Reference: GTX16649
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voltage independent potassium channel; activated by intracellular calcium [RGD, Feb 26]
Reference: GTX16650
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This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by...
Reference: GTX16651
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inward rectifier potassium channel [RGD, Feb 26]
Reference: GTX16652
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an acid-sensing K(+) channel; highly sensitive to changes in extracellular pH [RGD, Feb 26]
Reference: GTX16653
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This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the...
Reference: GTX16654
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voltage gated potassium channel pore-forming (alpha) subunit [RGD, Feb 26]
Reference: GTX16655
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tandem-pore K(+) channel that is a mechanosensitive and fatty acid-stimulated K(+) channel [RGD, Feb 26]
Reference: GTX16656
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may play a role in generation of neuronal pacemaker activity [RGD, Feb 26]
Reference: GTX16665
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This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target...
Reference: GTX16666
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mouse homolog is a subunit of the large conductance calcium-dependent potassium channel; downregulates channel activity [RGD, Feb 26]
Reference: GTX16667
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This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X....

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