Quote ACER2 antibody, Internal
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 26 [PubMed 1694153]).[supplied by OMIM, Jul 21]
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Reference:
GTX16556
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