Category: Biochemicals

Active filters

m-PEG-mal (MW 5000)

Reference: HY-140690

m-PEG-mal (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

rel-Paroxetine hydrochloride

Reference: HY-151216S

rel-Paroxetine-d4 (hydrochloride) is an isotope-labeled Paroxetine hydrochloride (HY-B0492). Paroxetine hydrochloride is an orally active and selective serotonin-reuptake inhibitor, commonly prescribed as an GRK2 inhibitor with IC50 of 14 μM. Paroxetine hydrochloride can be used for the research of depressive disorder[1][2][3][4].

c-Met-IN-10

Reference: HY-146274

c-Met-IN-10 (compound 26a) is a highly potent c-Met kinase inhibitor with an IC50 value of 16 nM. c-Met-IN-10 has inhibitory activity against cancer cells A549, H460 and HT-29 with IC50s of 0.56 ~ 1.59 μM. c-Met-IN-10 suppresses the colony formation on HT-29 cells, induces HT-29 and A549 cells apoptosis, and inhibits A549 cells motility. c-Met-IN-10 can be used for researching anticancer.

rel-Ritonavir-d6

Reference: HY-90001S3

rel-Ritonavir-d6 (rel-ABT 538-d6; rel-RTV-d6) is the deuterium labeled Ritonavir (HY-90001). Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.

m-PEG-thiol (MW 5000)

Reference: HY-140707

m-PEG-thiol (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

m-PEG-acrylate (MW 20000)

Reference: HY-140672

m-PEG-acrylate (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

m-Chloramphenicol

Reference: HY-136434

m-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis.

c-Met-IN-12

Reference: HY-147695

c-Met-IN-12 (compound 4r) is an orally active, potent and selective type II c-Met kinase inhibitor, with an IC50 of 10.6 nM. c-Met-IN-12 displays high inhibitory effects (inhibition rate > 80% in 1 μM) against AXL, Mer and TYRO3 kinases. c-Met-IN-12 can be used a scaffold for further kinase selectivity enhancement. c-Met-IN-12 shows antitumor efficacy.

Back to top