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Reference: 10649-250

An anthelmintic mitochondrial uncoupler; inhibits STAT3 (IC50 = 0.25 μM) and stimulates autophagy; induces mitochondrial uncoupling, activates AMPK, and increases lipid peroxidation in vitro at 1 µM; prevents high-fat diet-induced hepatic steatosis and insulin resistance and improves glycemic control in db/db mice at 125 mg/kg per day; inhibits proliferation and colony formation of DU145 prostate cancer cells (IC50s = 0.7 and 0.1 µM, respectively)

Reference: A3823-10

USP1 inhibitor

Reference: 252-10130

Prepared from cultures grown in medium completely devoid of animal based components and designed for bioprocessing applications where introduction of animal derived pathogens must be prevented.

Reference: 10649-50

An anthelmintic mitochondrial uncoupler; inhibits STAT3 (IC50 = 0.25 μM) and stimulates autophagy; induces mitochondrial uncoupling, activates AMPK, and increases lipid peroxidation in vitro at 1 µM; prevents high-fat diet-induced hepatic steatosis and insulin resistance and improves glycemic control in db/db mice at 125 mg/kg per day; inhibits proliferation and colony formation of DU145 prostate cancer cells (IC50s = 0.7 and 0.1 µM, respectively)

Reference: A3823-25

USP1 inhibitor

FSB

Reference: 10651-5

A fluorescent probe; has been used for the detection of amyloid plaques in human postmortem brain from patients with Alzheimer’s disease and of curli amyloid fibers in E. coli biofilms; has been used to label tau inclusions in mouse and human brain sections and in mouse spinal cord following intravenous injection; ex/em = 390/520 nm, respectively

Reference: A3823-50

USP1 inhibitor