Category: Reagents

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Reference: 252-10106

A highly purified preparation supplied as a lyophilized powder.

Reference: 10631-5

A small molecule activator of AMPK that stimulates functional activation of AMPK in cultured muscle cells (EC50 = 4.3 μM), enhancing glucose uptake by 3.2-fold; 10 mg/kg up-regulates the activity of AMPK in the liver and muscle of diet-induced obese mice, enhancing insulin sensitivity and increasing the oxidation of adipose tissues

Reference: 252-10111

Three times crystallized and treated with 1-chloro-3-tosylamido-7-amino-2-heptanone (TLCK) to inhibit trypsin activity [Shaw, et al., Biochemistry, 4, 2219, (1965)]. Dialyzed to remove autolysis products and low molecular weight contaminants. Supplied as lyophilized powder.

Reference: 10638-1

,An inhibitor of JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM); blocks signaling from IFN-α or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells

Reference: 252-10113

Chromatographically purified. Less than 50 caseinase units per milligram. Supplied as a lyophilized powder.

Reference: 10638-10

,An inhibitor of JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM); blocks signaling from IFN-α or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells

Reference: A3817-50

PDE5 inhibitor, selective