Deferiprone Reference: 20387-1 An iron chelator that binds to iron in a 3:1 (ligand:iron) ratio and has antioxidant and neuroprotective activities; reduces levels of intracellular iron and inhibits lipid peroxidation in primary rat hepatocytes at 200 and 50 µM, respectively; reduces cholesterol diet-induced increases in the levels of Aβ42, Aβ40, and the phosphorylation of tau and GSK-3β in the rabbit hippocampus at 50 mg/kg
Deferiprone Reference: 20387-10 An iron chelator that binds to iron in a 3:1 (ligand:iron) ratio and has antioxidant and neuroprotective activities; reduces levels of intracellular iron and inhibits lipid peroxidation in primary rat hepatocytes at 200 and 50 µM, respectively; reduces cholesterol diet-induced increases in the levels of Aβ42, Aβ40, and the phosphorylation of tau and GSK-3β in the rabbit hippocampus at 50 mg/kg
Deferiprone Reference: 20387-5 An iron chelator that binds to iron in a 3:1 (ligand:iron) ratio and has antioxidant and neuroprotective activities; reduces levels of intracellular iron and inhibits lipid peroxidation in primary rat hepatocytes at 200 and 50 µM, respectively; reduces cholesterol diet-induced increases in the levels of Aβ42, Aβ40, and the phosphorylation of tau and GSK-3β in the rabbit hippocampus at 50 mg/kg
Flecainide (acetate) Reference: 20388-10 An inhibitor of cardiac late INa channels (IC50 = 3.4 µM) and IKr channels (IC50 = 1.5 µM); used clinically to suppress arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure
Flecainide (acetate) Reference: 20388-25 An inhibitor of cardiac late INa channels (IC50 = 3.4 µM) and IKr channels (IC50 = 1.5 µM); used clinically to suppress arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure
Flecainide (acetate) Reference: 20388-5 An inhibitor of cardiac late INa channels (IC50 = 3.4 µM) and IKr channels (IC50 = 1.5 µM); used clinically to suppress arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure