BML-278 Reference: 20209-1 An activator of SIRT1, SIRT2, and SIRT3 (EC150s = 1, 25, and 50 µM, respectively); arrests cell cycling at the G1/S phase, reduces senescence in primary human mesenchymal cells, and significantly increases mitochondrial density in murine C2C12 myoblasts
BML-278 Reference: 20209-10 An activator of SIRT1, SIRT2, and SIRT3 (EC150s = 1, 25, and 50 µM, respectively); arrests cell cycling at the G1/S phase, reduces senescence in primary human mesenchymal cells, and significantly increases mitochondrial density in murine C2C12 myoblasts
BML-278 Reference: 20209-25 An activator of SIRT1, SIRT2, and SIRT3 (EC150s = 1, 25, and 50 µM, respectively); arrests cell cycling at the G1/S phase, reduces senescence in primary human mesenchymal cells, and significantly increases mitochondrial density in murine C2C12 myoblasts
BML-278 Reference: 20209-5 An activator of SIRT1, SIRT2, and SIRT3 (EC150s = 1, 25, and 50 µM, respectively); arrests cell cycling at the G1/S phase, reduces senescence in primary human mesenchymal cells, and significantly increases mitochondrial density in murine C2C12 myoblasts
L-Quisqualic Acid Reference: 20211-1 A natural analog of glutamate that acts as an agonist at AMPA-selective and metabotropic glutamate receptors (EC50s = 170, 10, 40, and 29 nM at GluR-A, mGluR1, mGluR3, and mGluR5, respectively), as well as (GRIK4 (Ki = 6.43 nM)